Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Icosapent ethyl (Vascepa) and omega-3-acid ethyl esters (Lovaza) are both used to lower triglyceride levels in adults, but they have some key differences. Vascepa contains only one type of omega-3 fatty acid, while Lovaza contains two types: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Vascepa is typically taken twice a day, whereas Lovaza can be taken once or twice a day. Vascepa is also used to lower the risk of heart problems in people taking statins who have high triglycerides and other risk factors, while Lovaza is mainly used for very high triglyceride levels. Common side effects of Vascepa include muscle and bone pain, while Lovaza often causes burping and changes in taste. Both medications are available as lower-cost generics and should be taken with food.
Icosapent ethyl (Vascepa) contains omega-3 fatty acids from fish oil and is used to lower triglyceride (TG) levels in adults. When taken together with a statin, icosapent ethyl (Vascepa) can help protect the heart of certain people who are at high risk of heart disease. The medication is taken by mouth twice daily. Icosapent ethyl (Vascepa) is available as a brand-name capsule and also has generic alternatives. The most common side effects include muscle and bone pain, swelling in the arms and legs, and constipation.
Summary for Antilipemic
Prescription only
Omega-3-acid ethyl esters (Lovaza) is made up of two different omega-3 fatty acids: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). This medication is used to lower triglycerides (TG) levels in adults. It works best when you're also eating a low-cholesterol diet and engaging in regular exercise. Omega-3 acids (Lovaza) is taken by mouth once or twice per day with food. Some side effects include burping, upset stomach, and changes in your sense of taste.
Indications of Vascepa vs. Lovaza
Indications for
•Lower the risk of heart problems in adults also taking statins who have high triglyceride levels, and have heart disease or diabetes with at least 2 risk factors for heart disease
•Lower triglyceride levels in adults with very high triglycerides levels when taken together with a healthy diet
Indications for
•Add-on to diet for the treatment of high triglycerides (TG) in adults with TG levels greater than 500 mg/dL