Key takeaways
Trolamine salicylate (Aspercreme Original) and lidocaine (Lidoderm) are both topical medications used to relieve pain, but they belong to different medication classes. Trolamine salicylate is a topical non-steroidal anti-inflammatory drug (NSAID) used for minor aches and pains like arthritis and muscle strains. Lidocaine viscous is a local anesthetic used for temporary relief of pain or discomfort from cuts, burns, and other skin conditions, as well as joint or muscle pain. Trolamine salicylate is available over-the-counter in forms like cream, spray, and foam, while lidocaine comes as a patch and is avaiable as a prescription or an OTC. Trolamine salicylate is applied up to four times a day, whereas lidocaine is applied once daily for a 12-hour period. Both medications can cause skin irritation. Lidocaine can also cause a mild burning sensation where you applied the patch.
