Compare
Tradjenta vs. Glumetza

Tradjenta (linagliptin) is a prescription medication that's used along with a balanced diet and exercise to manage blood sugar levels in adults with Type 2 diabetes. It's a type of diabetes medication called a dipeptidyl peptidase-4 (DPP-4) inhibitor. The dose is 5 mg (1 tablet) that's taken by mouth once per day. Tradjenta (linagliptin) doesn't cause many side effects but can sometimes include runny nose, sneezing, and diarrhea. As of 2024, Tradjenta (linagliptin) is available as a brand-name medication only; there's no generic version yet.

• Improve blood sugar levels in adults with Type 2 diabetes (as an add-on to a nutritious diet and exercise routine)

• Common cold symptoms (runny nose, sneezing, coughing; 7%)
• Diarrhea (3%)
• Cough (2%)

Note: Side effects were reported by people who took Tradjenta (linagliptin) by itself or people who took Tradjenta (linagliptin) with other diabetes.

• Inflammation of the pancreas (pancreatitis)
• Risk for low blood sugar when taken with certain other diabetes medications
• Heart failure
• Severe joint pain
• Serious allergic reactions
• Severe skin reaction

Metformin ER (Glumetza) is a biguanide. It's used to control blood sugar levels in adults with Type 2 diabetes. Metformin ER (Glumetza) is taken by mouth, typically once daily with an evening meal. Some of the more common side effects of this medication include diarrhea and nausea. But metformin ER (Glumetza) is less likely to cause stomach-related side effects than metformin immediate-release (IR) tablets. Metformin ER (Glumetza) is available as both brand-name and generic versions.

• Type 2 diabetes in adults

Please note: These are common side effects of people who took metformin ER (Glumetza) and glyburide together

• Low blood sugar (dizziness, shaking; 14%)
• Diarrhea (13%)
• Nausea (7%)

• Lactic acidosis (too much acid in your body)
• Low vitamin B12 levels
• Risk of low blood sugar levels