Key takeaways
Renova (tretinoin) and calcipotriene (Dovonex) are both topical medications, but they are used for different skin conditions. Renova is a retinoic acid derivative, a form of vitamin A, and is used to lessen fine wrinkles on your face. In contrast, calcipotriene is a vitamin D analog used to treat plaque and scalp psoriasis by slowing down the growth of skin cells. Renova is applied once daily in the evening, while calcipotriene can be applied once or twice daily depending on the form (cream, ointment, foam, or solution). Renova can cause skin irritation and makes your skin more sensitive to sunlight, requiring the use of sunscreen. Calcipotriene also causes skin irritation and shouldn’t be used on the face, but it is generally safe with fewer side effects. Both medications require a prescription and aren’t suitable for use during pregnancy.
