Key takeaways
Renova (tretinoin) and Botox Cosmetic (onabotulinumtoxinA) are both prescription medications used to improve the appearance of facial lines and wrinkles. However, they belong to different medication classes and work in distinct ways. Renova is a topical retinoic acid derivative applied to the skin to lessen fine facial wrinkles, while Botox Cosmetic is a neuromuscular blocker injected into muscles to temporarily improve frown lines, forehead lines, and crow's feet. Renova is applied once daily in the evening, whereas Botox Cosmetic is administered by a healthcare professional every three months. Renova is only available as a brand-name cream, while Botox Cosmetic is also brand-name only and comes as an injection. Common side effects of Renova include skin irritation, peeling, and redness, while Botox Cosmetic can cause droopy eyelids, headache, and muscle weakness. Additionally, Renova can make your skin more sensitive to sunlight, whereas Botox Cosmetic has risks related to the spread of toxin effects, which can lead to serious side effects like difficulty swallowing or breathing.
