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Remicade vs. Entyvio

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Infliximab (Remicade) and vedolizumab (Entyvio) are both disease-modifying antirheumatic drugs (DMARDs) used to treat autoimmune conditions like ulcerative colitis (UC) and Crohn's disease (CD). However, they have some important differences. Infliximab works by blocking tumor necrosis factor (TNF) to reduce inflammation. Vedolizumab, on the other hand, is an integrin antagonist that blocks proteins on immune cells to lower inflammation. Infliximab is administered as an intravenous (IV) infusion, while vedolizumab can be given either as an IV infusion or a subcutaneous injection. Infliximab is also used for conditions like rheumatoid arthritis and psoriasis, whereas vedolizumab is specifically for UC and CD in adults. Common side effects of infliximab include infections and infusion-related reactions, while vedolizumab may cause headaches and joint pain. Both medications can increase the risk of serious infections, but infliximab also has a risk of causing cancer and heart problems.

Remicade

(infliximab)

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Entyvio

(vedolizumab)

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Summary for Remicade

Prescription only

Remicade (infliximab) is an injectable medication used to treat many autoimmune conditions, including ulcerative colitis and Crohn's disease. It's given through an intravenous (IV) infusion by a healthcare provider.

Indications for Remicade

  • Moderate-to-severe Crohn's disease (CD)
  • Moderate-to-severe ulcerative colitis (UC)
  • Moderate-to-severe rheumatoid arthritis (RA)
  • Ankylosing spondylitis (AS)
  • Psoriatic arthritis (PsA)
  • Severe plaque psoriasis (PsO)

Pros and Cons for Remicade

Pros

  • Can be used for many autoimmune conditions
  • Typically only needs to be given every 6 to 8 weeks
  • Can be used in children 6 years of age and older for UC and CD

Cons

  • Can only be given as an IV infusion by a healthcare professional
  • Can cause a lot of side effects
  • Brand name only, which can be expensive

Common Side Effects for Remicade

  • Infections
  • Nausea
  • Infusion-related reactions (e.g., headache, flushing, shortness of breath, rash)
  • Headache
  • Diarrhea
  • Stomach pain
  • Sore throat
  • Cough
  • Rash
  • Bronchitis
  • Indigestion
  • Tiredness
  • General pain
  • Joint pain

Warnings for Remicade

  • Serious or deadly infections
  • Cancer
  • Liver problems and liver failure
  • Heart problems
  • Low blood cell counts
  • Nervous system problems
  • Medications to avoid

Summary for Entyvio

Prescription only

Entyvio, the brand name for vedolizumab, is an injection used to treat ulcerative colitis (UC) and Crohn's disease (CD) in adults. It belongs to a drug class called integrin antagonists that helps lower inflammation in the gut. Entyvio (vedolizumab) is an infusion that's given through the vein by a healthcare professional. After the first 2 doses, it's usually given every 2 months. If it works well, people can switch to injections under the skin every 2 weeks using prefilled syringes or pens. Side effects include headache, mild infections, and joint pain.

Indications for Entyvio

Pros and Cons for Entyvio

Pros

  • Have the option for infusions through the vein or injections under the skin after 6 weeks of treatment
  • Comes as prefilled syringes and pens for injections under the skin that can be given at home

Cons

  • IV infusions can only be given by a healthcare professional at a medical office
  • Can raise your risk of serious side effects, like infusion reactions and infections

Common Side Effects for Entyvio

Warnings for Entyvio

  • Infusion-related reactions and allergic reactions
  • Risk of serious infections
  • Risk of brain infection (progressive multifocal leukoencephalopathy)
  • Liver problems

Prices with our coupons for Remicade vs. Entyvio

Price Card Drug Icon
Remicade4 vials / 100mg
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Entyvio2 cartons / prefilled pen of 108mg/0.68ml
$6,993.40$9,943.80
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