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Nimodipine vs. Sular

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Nimodipine (Nymalize) and nisoldipine (Sular) are both calcium channel blockers (CCBs), but they are used for different conditions. Nimodipine is used to prevent brain damage after an aneurysmal subarachnoid hemorrhage, while nisoldipine is used to treat high blood pressure (hypertension). Nimodipine is taken as an oral capsule or liquid every 4 hours for 3 weeks, while nisoldipine is taken as an oral tablet once daily. Both medications are available as a brand and a lower-cost generic. Nimodipine can cause low blood pressure and diarrhea, while nisoldipine can cause swelling in the legs, feet, or hands, and headaches. Both medications have a number of interactions, including with grapefruit juice. Nimodipine is used in a hospital setting at first.

Nimodipine

(Nymalize)

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Nisoldipine

(Sular)

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Summary for Nimodipine

Prescription only

Nimodipine (Nymalize) is used to help prevent brain damage after an aneurysmal subarachnoid hemorrhage (a type of brain bleed). Your provider will typically start this medication in the hospital as soon as possible, but usually within 4 days of a subarachnoid hemorrhage. Nimodipine (Nymalize) is taken by mouth or given through a feeding tube every 4 hours for 3 weeks. Generic nimodipine comes as an oral capsule, while brand name Nymalize (nimodipine) comes as an oral liquid. The most common side effect of nimodipine (Nymalize) is low blood pressure, so your provider will check your blood pressure regularly while you're taking this medication.

Indications for Nimodipine

  • Prevention of brain damage after a type of brain bleed called an aneurysmal subarachnoid hemorrhage (aSAH)

Pros and Cons for Nimodipine

Pros

  • Prevents worsening of brain function after brain bleed
  • Available in liquid form if you can't swallow the capsule
  • Treatment typically lasts 3 weeks
  • Low risk of serious side effects

Cons

  • Can interact with some common medications and supplements
  • Needs to be taken every 4 hours
  • Needs to be taken on an empty stomach
  • Can lower blood pressure and cause dizziness

Common Side Effects for Nimodipine

  • Low blood pressure (4%)
  • Diarrhea (2%)
  • Rash (2%)
  • Stomach irritation (2%)

Warnings for Nimodipine

  • Take by mouth only
  • Low blood pressure
  • Medication interactions

Summary for Sular

Prescription only

Nisoldipine (Sular) is a type of blood pressure medication called a calcium channel blocker. It treats high blood pressure (hypertension) in adults. The extended-release tablets are taken by mouth once per day on an empty stomach. Some side effects include swelling in the arms or legs and headache. Nisoldipine (Sular) is available as a brand-name and generic medication.

Indications for Sular

Pros and Cons for Sular

Pros

Cons

Common Side Effects for Sular

  • Swelling in the legs, feet, or hands (22%)
  • Headache (22%)

Warnings for Sular

  • Severely low blood pressure
  • Risk of heart attack and chest pain
  • Allergic reaction

Prices with our coupons for Nimodipine vs. Sular

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Nimodipine90 capsules / 30mg
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Nisoldipine90 tablets / 8.5mg
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