Key takeaways
Ibuprofen (Advil, Motrin) and acetaminophen (Tylenol) are both used to relieve pain and reduce fever, but they work differently and have different side effects. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps with inflammation, swelling, and pain by blocking proteins called cyclooxygenase (COX). It can cause side effects like stomach pain, heartburn, and nausea, and it has risks for stomach bleeding, heart problems, and kidney issues. Acetaminophen, on the other hand, is an analgesic that works by stopping certain chemicals in the brain and nervous system. It doesn't help with inflammation and has fewer side effects, but it can cause severe liver damage if taken in high doses or with alcohol. Both medications are available over the counter, but ibuprofen also comes in prescription strengths. While ibuprofen is not recommended during the later stages of pregnancy, acetaminophen is generally considered safer for pregnant women. Always follow the dosing instructions and talk to a healthcare professional if you have any concerns.
