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Compare Tylenol vs. Vicoprofen

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Acetaminophen (Tylenol) and hydrocodone/ibuprofen (Vicoprofen) are both used to relieve pain, but they work in different ways and have different uses. Acetaminophen (Tylenol) is an over-the-counter analgesic that helps with mild pain and fever. It is available in various forms like tablets, liquids, and suppositories. While acetaminophen is generally safe with few side effects, it can cause liver damage if taken in high doses or with alcohol. Hydrocodone/ibuprofen (Vicoprofen), on the other hand, is a prescription-only combination of an opioid (hydrocodone) and a nonsteroidal anti-inflammatory drug (NSAID) (ibuprofen). It is used for more severe pain that non-opioid medications can't relieve. Hydrocodone/ibuprofen has more serious risks, including addiction, slowed breathing, and stomach bleeding. It requires careful monitoring due to these risks and is considered a Schedule II controlled medication due to its potential for misuse. Both medications have generic forms available, helping to make them more affordable.

  • Acetaminophen (Tylenol)
    Hydrocodone/ibuprofen
  • Acetaminophen (Tylenol)
    Hydrocodone/ibuprofen

  • Summary of Tylenol vs. Vicoprofen

    Summary for Analgesic

    Acetaminophen (Tylenol) is an over-the-counter (OTC) medication used to lower fever and relieve mild pain in adults and children. It's available in many strengths and formulations, such as tablets, chewable tablets, and liquid. In general, acetaminophen (Tylenol) works within 45 minutes when it's taken by mouth. This medication typically doesn't have many side effects. It's recommended to limit or avoid alcohol while taking acetaminophen (Tylenol) to lower your risk for liver problems.

    Summary for Opioid / NSAID
    Prescription only

    Hydrocodone/ibuprofen is a combination opioid medication that's used to treat pain when non-opioid medications don't provide enough relief. Your provider will discuss with you about your specific needs for pain relief to determine your dosage. Hydrocodone/ibuprofen can commonly cause side effects like headache, sleepiness, and constipation. This medication also has many serious warnings, such as slowed breathing, risk of misuse and dependency, and stomach bleeding. Although the brand name (Vicoprofen) is no longer available, the generic form is still on the market.

  • Indications of Tylenol vs. Vicoprofen

    Indications for
    •Mild pain
    •Fever
    Indications for
    •Pain that isn't relieved with non-opioid pain medications - used as short-term treatment (for less than 10 days)

  • Pros and Cons of Tylenol vs. Vicoprofen

    Pros and Const for Analgesic
    Pros
    •Works well to relieve mild aches or pain and lower fever
    •Can use in adults and children
    •Available in a lower-cost generic and is available over the counter
    •Comes in many different strengths and forms (e.g., tablet, capsule, chewable tablet, liquid, powder, suppository)
    Cons
    •Doesn't help with inflammation and swelling
    •Might not work as well to treat moderate-to-severe pain
    •Not the best option for people who drink alcohol often because of the risk of liver damage
    Pros and Const for Opioid / NSAID
    Pros
    •Helps relieve pain that isn't well-controlled with non-opioid pain medications alone
    •Combines two different medications to ease pain in different ways
    •Might start to notice pain relief in 30 minutes
    •Available in a lower-cost, generic form
    Cons
    •Can cause serious slow breathing and stomach and heart problems
    •Shouldn't use with other NSAID medications
    •Is a controlled substance because of the risk of misuse and dependency so there are special requirements to getting a prescription filled

  • Common Side Effects of Tylenol vs. Vicoprofen

    Common Side Effects for

    Side effects typically aren't common with this medication.

    Common Side Effects for
    •Headache (27%)
    •Constipation (22%)
    •Nausea (21%)
    •Sleepiness or tiredness (22%)
    •Dizziness (14%)
    •Indigestion (12%)

  • Warnings of Tylenol vs. Vicoprofen

    Common Side Effects for
    •Liver damage
    •Accidental overdose
    •Allergic skin reactions
    Common Side Effects for
    •Potential for addiction and misuse
    •Potentially deadly slowed breathing (respiratory depression)
    •Risk of accidental overdose
    •Blood clots, heart attack, or stroke
    •Stomach bleeding and ulcers
    •Interactions with other medications
    •Harm to newborn babies
    •Severely low blood pressure
    •High blood pressure, swelling, and heart failure
    •Kidney damage and high potassium levels
    •Liver problems
    •Low hormone levels
    •Higher risk of seizures in people with seizure conditions
    •Physical dependence and withdrawal
    •Serious allergic reaction and skin reactions
    •Asthma attack in people with asthma

  • Prices with our coupons for Tylenol vs. Vicoprofen

    Learn more about Acetaminophen
    Learn more about Hydrocodone/ibuprofen

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