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Hydrocodone / Ibuprofen Coupon - Hydrocodone / Ibuprofen 7.5mg/200mg tablet

hydrocodone / ibuprofen

Generic Vicoprofen
Used for Pain
Used for Pain

Hydrocodone/ibuprofen is a combination opioid medication that's used to treat pain when non-opioid medications don't provide enough relief. Your provider will discuss with you about your specific needs for pain relief to determine your dosage. Hydrocodone/ibuprofen can commonly cause side effects like headache, sleepiness, and constipation. This medication also has many serious warnings, such as slowed breathing, risk of misuse and dependency, and stomach bleeding. Although the brand name (Vicoprofen) is no longer available, the generic form is still on the market.

Last reviewed on September 17, 2023
Hydrocodone/ibuprofen is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.
basics-icon

What is Hydrocodone/ibuprofen?

What is Hydrocodone/ibuprofen used for?

How Hydrocodone/ibuprofen works

Hydrocodone/ibuprofen is a combination of two medications.

  • Hydrocodone is an opioid medication that attaches to proteins in your brain called mu-opioid receptors to change how you react to pain. This helps lower how much pain you feel.

  • Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It blocks certain proteins that are involved in the inflammation process in your body. This helps relieves pain and swelling.

Are you looking for information on Norco (hydrocodone / acetaminophen) instead?
When does Hydrocodone/ibuprofen start working?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsVicoprofen (brand no longer available)
Drug ClassOpioid / NSAID
Controlled Substance ClassificationSchedule II
Generic StatusLower-cost generic available
AvailabilityPrescription only
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What are the risks and warnings for Hydrocodone/ibuprofen?

Hydrocodone/ibuprofen can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

risk-warning

Potential for addiction and misuse

  • Risk factors: Personal or family history of substance or alcohol abuse | History of mental health conditions (like depression)

    Hydrocodone/ibuprofen has a risk for addiction and misuse because it contains hydrocodone (an opioid). Addiction can develop even at recommended doses as prescribed or when hydrocodone/ibuprofen is used for reasons other than prescribed (misuse). Sometimes, addiction and misuse can lead to life-threatening overdose. To lower the risk for addiction and misuse, your provider will prescribe the lowest amount of hydrocodone/ibuprofen that's necessary for you for the shortest period of time possible.

    Because of the risk for addiction and misuse, the FDA requires a Risk Evaluation and Mitigation Strategy (REMS) program for hydrocodone/ibuprofen. Under the Opioid Analgesic REMS program, your provider will talk to you about how to take hydrocodone/ibuprofen safely, what its risks are, and proper storage and disposal. These steps help keep you and your loved ones safe. Talk to your provider about other treatment options for pain if you have concerns about taking hydrocodone/ibuprofen.

    risk-warning

    Potentially deadly slowed breathing (respiratory depression)

    • Risk factors: Age 65 years or older | Severe breathing problems like chronic obstructive pulmonary disease (COPD) | Sleep-related breathing problems (e.g., apnea) | Head injury | Severe weakness or muscle loss | Drinking alcohol | Taking medications that slow your body down | Taking high doses of hydrocodone/ibuprofen

      Opioids like hydrocodone can cause extremely slowed breathing that can be deadly. This can happen at any time, even when the medication is used as recommended by your provider. But the risk is generally highest when you first start the medication or after your dose is raised. Don't take hydrocodone/ibuprofen with alcohol or other medications that can slow your body down (e.g., benzodiazepines, muscle relaxants). Doing so can slow down your breathing even more. Get medical help or call 911 right away if you or a loved one notices that you have trouble breathing; slow and shallow breathing; or bluish-colored lips, fingers, or toes.

      risk-warning

      Risk of accidental overdose

      • Risk factors: History of opioid use disorder | Previous opioid overdose | Taking medications that can slow the body down | Alcohol use | Taking high opioid doses | Taking more opioids than prescribed | Age 65 years or older | Age 18 years or younger

        It's possible to accidentally take too much hydrocodone/ibuprofen, even at recommended doses of the medication. Overdoses can also happen if it's accidentally taken by a child or a loved one. Overdoses can be life-threatening if it's not recognized or treated in time. Your provider might recommend that you carry naloxone (Narcan) with you at all times to quickly, but temporarily reverse the effects of the medication if an accidental overdose happens. It's important for you and your caregiver to know how to use naloxone (Narcan) in case this happens. Opioid overdose symptoms include extremely slowed breathing, slow heartbeat, extreme sleepiness, cold or clammy skin, and not responding to sound or touch. Call 911 right away if you think an overdose has happened.

        risk-warning

        Blood clots, heart attack, or stroke

        • Risk factors: History of heart problems | Recent heart attack | Heart bypass surgery in the last two weeks | Planned heart bypass surgery | Taking hydrocodone/ibuprofen for a long time

          Hydrocodone/ibuprofen can raise your risk of having blood clots, heart attack, and stroke. Talk to your provider before starting this medication if you have heart problems, especially if you've recently had a heart attack or heart bypass surgery. To lower your risk, take hydrocodone/ibuprofen at the lowest dose and for the shortest amount of time possible. Don't take hydrocodone/ibuprofen if you've recently had or will be having heart surgery. Call 911 if you experience chest pain, trouble breathing, weakness on one side of your body, or trouble speaking or walking.

          risk-warning

          Stomach bleeding and ulcers

          • Risk factors: Older adults | History of stomach bleeding or ulcers | Bleeding problems | Liver problems | Taking other medications that raise your risk for bleeds | Drinking alcohol | Smoking | Having poor health | Taking hydrocodone/ibuprofen for a long time

            NSAIDs like ibuprofen can raise your risk for serious bleeding,ulcers, and tears in the stomach, gut, or esophagus (tube that leads from your mouth to your stomach). In some cases, this can be life-threatening. Serious stomach or gut problems can happen without warning while you're taking hydrocodone/ibuprofen. Your risk for stomach bleeds might be higher if you're also taking other medications that can cause bleeding, such as oral corticosteroids, blood thinners (anticoagulants), and other NSAIDS like aspirin.

            Make sure your provider is aware of all of your medical conditions and medications before starting hydrocodone/ibuprofen so they can discuss with you about your risk for stomach or gut bleeds. Get medical help right away if you have severe stomach pain, black and tarry stools, or blood in your vomit or urine while using hydrocodone/ibuprofen.

            risk-warning

            Interactions with other medications

            Certain medications can interfere with how well your body gets rid of hydrocodone/ibuprofen. This can affect the amount of hydrocodone/ibuprofen in your body, how well it works, and the risk of side effects.

            Some medications, like erythromycin (Ery-Tab) and ritonavir (Norvir), can raise the levels of hydrocodone/ibuprofen in your body. Higher levels can lead to potentially deadly slowed breathing. Other medications, such as rifampin (Rifadin) and carbamazepine (Tegretol), can lower the levels of hydrocodone/ibuprofen in your body. This can cause the pain medication to not work as well and lead to withdrawal.

            If you're already taking stable doses of hydrocodone/ibuprofen with one of these other medications, don't stop taking them suddenly. Doing so can lead to unsafe hydrocodone/ibuprofen levels. Let your provider or pharmacist know what other medications you’re taking before starting hydrocodone/ibuprofen to make sure your medications are safe for you.

            risk-warning

            Harm to newborn babies

            • Risk factors: Long-term use during pregnancy | Currently in second or third trimester of pregnancy

              If you take opioids (like hydrocodone in hydrocodone/ibuprofen) for a long period of time during pregnancy, there's a risk that your unborn baby can become dependent on the medication. Once born, your baby can develop a condition called neonatal opioid withdrawal syndrome (NOWS) and experience withdrawal symptoms. Withdrawal symptoms in your newborn can include high-pitched crying, poor feeding and sucking behavior, trembling, irritability, and sometimes seizures. This condition can be life-threatening if not recognized and treated in time.

              In addition, this medication can can cause harm to your unborn baby if it's taken after 20 weeks of pregnancy. NSAIDs (like ibuprofen in hydrocodone/ibuprofen) can cause serious complications, such as heart or kidney problems in your unborn baby, if they're taken during the second half of pregnancy.

              Speak to your provider about the risks and benefits of taking hydrocodone/ibuprofen if you're pregnant. Let your provider know if you've used this medication during pregnancy or if you notice withdrawal symptoms in your baby. Ask whether there are safer alternatives.

              risk-warning

              Severely low blood pressure

              • Risk factors: Age 65 years or older | Taking other medications that lower blood pressure or slow your body down| Dehydration or loss of body fluid through severe vomiting, bleeding, or diarrhea

                Hydrocodone/ibuprofen can cause extremely low blood pressure, including a sudden drop in blood pressure when you stand from a sitting or lying down position. As a result, you might feel dizzy or even faint. To avoid falling, get up slowly if you've been sitting or lying down. If dizziness or lightheadedness doesn't go away, talk to your provider.

                risk-warning

                High blood pressure, swelling, and heart failure

                NSAIDs (like ibuprofen in hydrocodone/ibuprofen) can raise your blood pressure or cause swelling in the arms or legs. It can also put you at risk for heart failure or hospitalization from heart failure complications. This is because NSAIDs can cause your body to hold onto extra fluid. Some blood pressure or heart failure medications might not work as well when taken with hydrocodone/ibuprofen. Let your provider know if you have any heart problems (especially heart failure) or if you're taking medications for these conditions so they can make sure hydrocodone/ibuprofen is safe for you.

                Check your blood pressure regularly while you're taking hydrocodone/ibuprofen, and let your provider know if you notice any changes. Also contact your provider if you experience trouble breathing, tiredness, swelling in your body, or sudden weight gain as these can be symptoms of heart failure.

                risk-warning

                Kidney damage and high potassium levels

                • Risk factors: Older adults | Kidney or liver problems | Heart failure | Taking certain blood pressure medications (e.g., water pills, ACE inhibitors, ARBs) | Loss of body fluid through severe vomiting, bleeding, or diarrhea | Using hydrocodone/ibuprofen for a long time

                  Taking hydrocodone/ibuprofen for a long time can damage your kidneys by lowering blood flow to the kidneys. The risk of kidney damage is higher if you're taking certain blood pressure medications (like ACE inhibitors, ARBs, or water pills). Your risk might also be higher if you have certain medical conditions, such as kidney problems, liver problems, and heart failure. Kidney damage is usually reversible once you stop taking hydrocodone/ibuprofen. Tell your provider if you notice a change in how often you urinate after starting this medication since this can be a sign of kidney damage.

                  In addition, kidney damage from NSAIDs like ibuprofen can lead to high potassium levels. Sometimes, NSAIDs can cause high potassium levels even in people with healthy kidneys. Call your provider right away if you experience symptoms of high potassium levels, such as nausea, vomiting, muscle weakness, or tingling in your limbs because it can lead to dangerous health problems.

                  risk-warning

                  Liver problems

                  Some people have had liver damage while taking NSAIDs like the ibuprofen in hydrocodone/ibuprofen. Although rare, this liver damage can be life-threatening. Stop taking this medication and contact your provider right away if you experience signs and symptoms of liver problems, such as nausea, fatigue, itchiness, yellowing of your skin of whites of your eyes, pain on the upper right side of your stomach, or flu-like symptoms.

                  risk-warning

                  Low hormone levels

                  Some people taking opioid medications like hydrocodone/ibuprofen experienced a drop in their hormone levels. This is more likely to happen if you take the medication for more than a month. Symptoms of low hormone levels include nausea, loss of appetite, tiredness, weakness, and dizziness. Let your provider know if you have these symptoms.

                  risk-warning

                  Higher risk of seizures in people with seizure conditions

                  • Risk factors: History of seizures

                    Opioids, such as hydrocodone in hydrocodone/ibuprofen, can more frequent seizures to happen in people who've had seizures in the past. The medication might also raise the risk of seizure in other situations where seizures can occur. Let your healthcare provider know if you have seizures more often while you're taking hydrocodone/ibuprofen.

                    risk-warning

                    Physical dependence and withdrawal

                    • Risk factors: Long-term use of hydrocodone/ibuprofen

                      If you take hydrocodone/ibuprofen regularly for a long time, you can become physically dependent on the medication. This means your body starts to rely on the medication to function. And you might experience withdrawal if you suddenly lower your dose or stop taking the medication. Withdrawal symptoms can include restlessness, muscle pain, runny nose, yawning, sweating, chills, anxiety, and uncontrolled pain. Don't lower your dose or stop taking the medication suddenly without talking to your provider. To prevent withdrawal symptoms from happening, follow your provider's instructions carefully to slowly lower your dose. Talk to your provider about alternative pain medications if you have concerns about this risk.

                      risk-warning

                      Serious allergic reaction and skin reactions

                      Hydrocodone/ibuprofen can cause serious allergic reactions and skin reactions that can sometimes be life-threatening. Stop taking this medication and get medical help right away if you develop any type of rash, skin peeling, painful blisters, fever, swollen lymph nodes, facial swelling, trouble breathing, or anaphylaxis.

                      risk-warning

                      Asthma attack in people with asthma

                      • Risk factors: Asthma | Stuffy nose with or without nasal polyps | History of allergic reaction to aspirin or other NSAIDs

                        Be careful using hydrocodone/ibuprofen if you have asthma. You might have worsening asthma symptoms while you're taking hydrocodone/ibuprofen if you have asthma or if you've had asthma attacks after taking aspirin or another NSAID. Get medical help right away if your throat tightens and you can't breathe.

                        basics-icon

                        What are the side effects of Hydrocodone/ibuprofen?

                        The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

                        Common Side Effects

                        • Headache (27%)
                        • Constipation (22%)
                        • Nausea (21%)
                        • Sleepiness or tiredness (22%)
                        • Dizziness (14%)
                        • Indigestion (12%)

                        Other Side Effects

                        • Stomach pain
                        • Vomiting
                        • Diarrhea
                        • Gas
                        • Dry mouth
                        • Anxiety
                        • Nervousness
                        • Weakness
                        • Trouble sleeping
                        • Body swelling (edema)
                        • Itchiness
                        • Sweating
                        • Infection

                        Serious Side Effects

                        Contact your healthcare provider immediately if you experience any of the following.
                        • Slowed breathing
                        • Accidentally taking too much (overdose): not responding to sound or touch; slowed breathing; slow heartbeat; severe sleepiness; pale, blue, cold, or clammy skin
                        • Heart problem (heart attack, heart failure): trouble breathing, chest pain or tightness, tiredness, swelling in your body, sudden weight gain
                        • Stroke: blurred vision, trouble speaking or walking, weakness on one side of the body, droopy face
                        • Stomach or gut bleed: blood in your vomit, stool that looks like black coffee grounds, pain in your stomach that doesn't go away
                        • Opioid withdrawal: restlessness, muscle or joint pain, runny nose, yawning or sweating more than usual, chills, irritability, anxiety
                        • Serious allergic reaction or skin reaction: reddening or peeling of the skin, painful rash, fluid-filled blisters, fever, facial swelling, trouble breathing
                        • Seizures
                        When do Hydrocodone/ibuprofen possible side effects begin and end?
                        Time passed since treatment started:
                        MINUTES
                        HOURS
                        DAYS
                        WEEKS
                        MONTHS
                        Sleepiness
                        Nausea or vomiting
                        Constipation
                        Slowed breathing
                        Seek immediate medical care if you experience this side effect.
                        If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

                        Source: DailyMed

                        The following side effects have also been reported

                        Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

                        Check with your doctor immediately if any of the following side effects occur:

                        Rare

                        Bloody stools

                        burning feeling in the chest or stomach

                        changes in facial skin color

                        cough

                        diarrhea

                        difficulty with swallowing

                        fast or irregular breathing

                        fever

                        frequent urge to urinate

                        heartburn

                        inability to urinate

                        irregular heartbeat

                        lightheadedness or dizziness

                        loss of bladder control

                        puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

                        ringing or buzzing in the ears

                        tightness in the chest

                        trouble breathing

                        skin rash, hives, or itching

                        stomach pain

                        tenderness in the stomach

                        visual disturbances

                        yellow eyes or skin

                        Incidence not known

                        Agitation

                        confusion

                        darkening of the skin

                        difficulty swallowing

                        dizziness

                        fainting

                        fever

                        loss of appetite

                        mental depression

                        nausea

                        overactive reflexes

                        poor coordination

                        puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

                        restlessness

                        shivering

                        talking or acting with excitement you cannot control

                        trembling or shaking

                        twitching

                        unusual tiredness or weakness

                        vomiting

                        Get emergency help immediately if any of the following symptoms of overdose occur:

                        Symptoms of overdose

                        Blurred vision

                        cold or clammy skin

                        confusion

                        difficulty hearing or ringing or buzzing in the ears

                        dizziness

                        general feeling of illness

                        headache

                        mood or mental changes

                        nausea

                        severe drowsiness

                        severe stomach pain

                        skin rash

                        slow heartbeat

                        stiff neck or back

                        swelling of the face, fingers, feet, or lower legs

                        vomiting

                        Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

                        More common

                        Anxiety

                        constipation

                        dry mouth

                        gas

                        increased sweating

                        nervousness

                        pounding heartbeat

                        sleepiness

                        trouble in sleeping

                        Rare

                        Decreased appetite

                        decrease in sexual ability

                        headache

                        heartburn

                        increased thirst

                        irritability

                        mood or mental changes

                        mouth ulcers

                        pain or burning in the throat

                        runny nose

                        sensation of burning, warmth, heat, numbness, tightness, or tingling

                        slurred speech

                        stomach upset

                        thinking abnormalities

                        unexplained weight loss

                        unusual feeling of well-being

                        Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

                        Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

                        pros-and-cons

                        Pros and cons of Hydrocodone/ibuprofen

                        thumbs-up

                        Pros

                        Helps relieve pain that isn't well-controlled with non-opioid pain medications alone

                        Combines two different medications to ease pain in different ways

                        Might start to notice pain relief in 30 minutes

                        Available in a lower-cost, generic form

                        thumbs-down

                        Cons

                        Can cause serious slow breathing and stomach and heart problems

                        Shouldn't use with other NSAID medications

                        Is a controlled substance because of the risk of misuse and dependency so there are special requirements to getting a prescription filled

                        pharmacist-tips

                        Pharmacist tips for Hydrocodone/ibuprofen

                        pharmacist
                        • Take hydrocodone/ibuprofen exactly as prescribed by your provider. Taking the medication any differently than it's prescribed can cause side effects or an accidental overdose.

                          • Hydrocodone/ibuprofen can cause sleepiness, dizziness, or lightheadedness, which can affect your ability to focus and think. Avoid driving or doing anything that requires your full attention until you know how hydrocodone/ibuprofen affects you to prevent accidentally hurting yourself or others.

                            • Don't mix hydrocodone/ibuprofen with alcohol, with any medication that contain alcohol, or with other medications that make you sleepy or react slower. Doing so can affect your ability to think clearly and lead to accidental injuries. It could even lead to a deadly overdose.

                              • Let your provider and pharmacist know about all the other medications you take or plan to take with hydrocodone/ibuprofen. They can check for potentially dangerous drug interactions and make sure your medications are safe for you to take. For example, taking hydrocodone/ibuprofen with certain antidepressants can put you at risk for serious side effects like serotonin syndrome.

                                • If you've taken hydrocodone/ibuprofen for a long period of time, don't suddenly lower your dose or stop taking the medication without talking to your provider first. Doing so can lead to withdrawal symptoms, like restlessness, body aches, trouble sleeping, and anxiety. Follow your provider's instructions to slowly cut back on your dose over a few weeks to prevent withdrawal.

                                  • Ask your provider or pharmacist about naloxone (Narcan), a medication that can help reverse the effects of accidentally taking too much hydrocodone/ibuprofen. It's important that you and your loved ones know when and how to use naloxone in case an accidental overdose happens. Still call for emergency medical help if you need to use naloxone because its effects can go away.

                                    • Keep hydrocodone/ibuprofen out of reach of children and in a location that can't be easily accessed by visitors to your home. If you no longer need the medication or if it's expired, throw the medication away through a take-back program or by flushing it down the toilet. This helps keep your loved ones safe from accidental overdose and prevent medication misuse.

                                      faqs

                                      Frequently asked questions about Hydrocodone/ibuprofen

                                      Can you take hydrocodone and ibuprofen together?
                                      Hydrocodone and ibuprofen are available as separate medications, as well as a combination medication (hydrocodone/ibuprofen). You shouldn't take them together as separate medications unless your provider instructed you to. As separate medications, hydrocodone and ibuprofen have strengths, dosages, and directions that are different than the combination product. Also keep in mind that hydrocodone and ibuprofen each have their own set of risks. Talk to your provider whether the hydrocodone/ibuprofen combination medication is right for you.
                                      How much ibuprofen is in the hydrocodone/ibuprofen combination medication?
                                      Each tablet of hydrocodone/ibuprofen contains 200 mg of ibuprofen. Keep in mind that many over-the-counter medications for colds, fever, and pain can also contain ibuprofen. Taking too much ibuprofen can can raise your risk of serious stomach problems and kidney damage. That's why it's recommended that you avoid taking medications that contain ibuprofen at the same time as hydrocodone/ibuprofen. Ask your provider or pharmacist if you're unsure whether your other medications contain ibuprofen.
                                      Is hydrocodone/ibuprofen a narcotic?
                                      Yes, hydrocodone/ibuprofen is considered a narcotic. Narcotics refer to opioids. And hydrocodone (one component of hydrocodone/ibuprofen) is an opioid medication.
                                      Can I drink alcohol with hydrocodone/ibuprofen?
                                      Avoid drinking alcohol while you're taking hydrocodone/ibuprofen. Both alcohol and hydrocodone/ibuprofen can slow your body down and cause slower breathing, sleepiness, dizziness, and "brain fog." Mixing alcohol with hydrocodone/ibuprofen can make these effects more intense and lead to accidental injuries or possibly even a life-threatening overdose. Speak with your provider if you have concerns about how much you drink. They can give guidance as to how to lower how much you drink and stop drinking altogether.
                                      Can I take ibuprofen (Advil) or naproxen (Aleve) while I'm taking hydrocodone/ibuprofen?
                                      It's not recommended that you take NSAIDs like ibuprofen (Advil) or naproxen (Aleve) while you're taking hydrocodone/ibuprofen. Hydrocodone/ibuprofen contains an NSAID (ibuprofen). Taking another NSAID together with hydrocodone/ibuprofen can raise your risk of serious stomach problems, and it might not help with your pain any more than with hydrocodone/ibuprofen alone. Keep in mind that NSAIDs can be found in many over-the-counter medications for colds, fever, and pain. Check with your provider or pharmacist if you're unsure whether a medication contains an NSAID or if you need to take low-dose aspirin. Ask your provider or pharmacist about other pain relievers that might be safer for you to take with hydrocodone/ibuprofen.
                                      Can I take acetaminophen (Tylenol) while I'm taking hydrocodone/ibuprofen?
                                      Yes. In fact, it's recommended that you take acetaminophen (Tylenol) if you need additional pain relief. Since acetaminophen (Tylenol) is a non-opioid pain medication, taking acetaminophen (Tylenol) can help lower the amount of hydrocodone/ibuprofen you take and lower the risks that come with taking opioids. Keep in mind that acetaminophen (Tylenol) also carries its own risks. So speak with your provider before taking acetaminophen (Tylenol) if your pain isn't controlled with hydrocodone/ibuprofen alone to see if this is appropriate for you.
                                      Can I take hydrocodone/ibuprofen if I'm pregnant?
                                      Talk to your provider about the risks and benefits of taking hydrocodone/ibuprofen during pregnancy. Taking this medication in the second half of pregnancy (20 weeks of pregnancy and later) can harm your unborn baby and cause serious complications, such as heart or kidney problems. In addition, taking hydrocodone/ibuprofen for a long period of time during pregnancy can cause withdrawal symptoms in your newborn baby. These withdrawal symptoms can include poor feeding or sucking, breathing problems, high-pitched crying, and even seizures. Withdrawal can be life-threatening if it's not recognized or treated. Your provider can discuss with you about possible alternatives that are safer for you and your baby.
                                      Will hydrocodone/ibuprofen affect my ability to have a baby?
                                      Using hydrocodone/ibuprofen long term can affect your fertility and make it harder for you to get pregnant. It isn't known whether this effect will go away after you stop taking hydrocodone/ibuprofen. This medication can also delay when your ovary releases an egg (ovulation). Talk to your provider if you have concerns about family planning while you're taking hydrocodone/ibuprofen.
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                                      dosage

                                      Hydrocodone/ibuprofen dosage forms

                                      The average cost for 90 tablets of 7.5mg/200mg of Hydrocodone/ibuprofen is $34.81 with a free GoodRx coupon. This is 73.23% off the average retail price of $130.03.
                                      tablet
                                      Tablet
                                      DosageQuantityPrice as low asPrice per unit
                                      5mg/200mg30 tablets$32.53$1.08
                                      7.5mg/200mg90 tablets$34.81$0.39
                                      10mg/200mg90 tablets$101.57$1.13

                                      Typical dosing for Hydrocodone/ibuprofen

                                      Your provider will work with you to find the right dose and treatment regimen for your individual needs. In general, it's recommended to use the lowest dose possible for the shortest duration of time to manage your pain.

                                      Each tablet contains 200 mg of ibuprofen and either 2.5 mg, 5 mg, 7.5 mg, or 10 mg of hydrocodone. The typical starting dose is 1 tablet by mouth every 4 to 6 hours on an as-needed basis for pain.

                                      interactions

                                      Interactions between Hydrocodone/ibuprofen and other drugs

                                      Hydrocodone/ibuprofen may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Hydrocodone/ibuprofen. Please note that only the generic name of each medication is listed below.

                                      Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                                      Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                      Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                      drug-cost

                                      How much does Hydrocodone/ibuprofen cost?

                                      To access savings, use a GoodRx coupon and pay just a fraction of the retail price.View prices & coupons
                                      contraindications-icon

                                      Hydrocodone/ibuprofen contraindications

                                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Hydrocodone/ibuprofen will not be safe for you to take.
                                      images

                                      Hydrocodone/ibuprofen images

                                      White Round Ip 145 - Hydrocodone Bitartrate / Ibuprofen 7.5mg-200mg Tablet
                                      This medicine is White, Round Tablet Imprinted With "Ip 145".White Round Ip 145 - Hydrocodone Bitartrate / Ibuprofen 7.5mg-200mg Tablet

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                                      References

                                      Best studies we found

                                      Amneal Pharmaceuticals of New York LLC. (2024). Hydrocodone bitartrate and ibuprofen tablet [package insert]. DailyMed.

                                      Centers for Disease Control and Prevention. (2022). About opioid use during pregnancy.

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                                      GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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