Featuring Jonathan Avery, MDReviewed by Mera Goodman, MD, FAAP | June 28, 2024

Using any sort of substance—alcohol, marijuana, cocaine, and so on—is inherently risky. These substances always come with the potential of addiction or dependency, or even substance use disorder.

That said, there are plenty of people who occasionally drink alcohol or dabble in marijuana products, but seem to have control over their usage. They can self-regulate their intake, stop before they’ve taken too much, and go days, weeks, or months without experimenting again.

“Certain folks, though, either from genetic predispositions or from having co-occurring mental health issues, [will] start using a substance, and then find it very hard to curb their use over time,” says Jonathan Avery, MD, director of Addiction Psychiatry at Weill Cornell Medicine and NewYork-Presbyterian Hospital.

Substance use disorder is a disease that leads to compulsive use of a substance despite impaired physical, mental, and social function. In other words, continued use of the substance is having harmful consequences, but you have a strong desire to continue use.

Of course, in reality, it’s harder to see where the line is between substance misuse and substance use disorder. Substance misuse simply refers to the harmful use of substances for non-medical purposes. There are plenty of ways people misuse substances: happy hours multiple times a week, occasional drug use, weekend hangovers, etc.

So when does it cross the line to a disorder?

“In general, the definition we look for is that when you're using a substance in a way that impairs your function over time, that's when we really think you're getting into trouble,” says Dr. Avery.

Signs of substance use disorder

Someone with substance use disorder may have behavioral changes (mood swings, agitation, apathy, secretiveness), physical changes (weight gain or loss, tremors, bloodshot eyes), or social changes (change in friends and hobbies, financial problems, relational conflicts).

Additionally, Dr. Avery suggests two major signs of substance use disorder. “One is you find [that] substance use becoming the answer to every question in your life,” says Dr. Avery. Using a substance becomes the thing you do after work, when you’re bored, when you’re hungry, when you’re lonely, and when you’re happy.

The other sign requires listening to comments by loved ones. “It's often the loved ones that are the first ones that are aware of this and say, ‘Hey, what's going on here?’” says Dr. Avery.

Substance use disorder, like other mental health issues, can be treated. It may involve a combination of rehabilitation, medications, psychotherapy, and group therapy or support groups. (Find out what to expect at your first therapy session here.)

References

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.