Key takeaways
Meloxicam (Mobic) and naproxen (Naprosyn) are both prescription non-steroidal anti-inflammatory drugs (NSAIDs) used to treat pain and inflammation. Meloxicam is available in various forms, including capsules, tablets, liquid, and injection, and is typically taken once a day. In contrast, naproxen comes as tablets and liquid suspension and is usually taken 2 to 3 times per day. Meloxicam primarily blocks COX-2 proteins, which may result in fewer stomach and kidney side effects compared to other NSAIDs. Naproxen blocks both COX-1 and COX-2 proteins and is known to cause side effects like heartburn and stomach pain. Both medications can raise the risk of stomach bleeding, heart attack, and stroke, and are not recommended during pregnancy, especially after 20 weeks. While meloxicam is generally taken for arthritis pain, naproxen can be used for acute pain relief, such as for gout attacks or menstrual cramps.
