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Meloxicam vs. Prednisone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Meloxicam and prednisone are both prescription medications used to treat conditions involving inflammation and pain, such as arthritis. However, they belong to different medication classes. Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking proteins that cause inflammation, while prednisone is a corticosteroid that lessens your body's immune response that otherwise causes symptoms such as pain, itching, and swelling. Meloxicam is available in various forms, including capsules, tablets, oral suspension, and an injection (administered by a healthcare professional only), and is typically taken once daily. Prednisone is available as immediate-release tablets, delayed-release tablets, and an oral solution, with dosing varying based on the condition being treated. Both medications are available as lower-cost generics. Common side effects of meloxicam include diarrhea and stomach upset, whereas prednisone can cause mood changes and increased appetite. Both medications have potential drug interactions; for example, meloxicam should not be taken with other NSAIDs, and prednisone should be used cautiously with medications that weaken the immune system.

Meloxicam

 

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Prednisone

 

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Summary for Meloxicam

Prescription only

Meloxicam is a prescription non-steroidal anti-inflammatory drug (NSAID). It's used for different types of arthritis pain. It comes as capsules, tablets and a liquid. All forms are for adults, but some are also for children of certain age and weight. Meloxicam is taken by mouth once a day. The dosage depends on your arthritis type, the form of meloxicam you're using, and age and weight for children. Common side effects include diarrhea, joint pain, and stomach upset. Like all NSAIDs, it can raise the risk of stomach bleeds. Meloxicam is a generic medication; its brand name Mobic is no longer available.

Indications for Meloxicam

Pros and Cons for Meloxicam

Pros

Cons

  • Available by prescription only
  • Might not be the best option for older adults or people with kidney, heart, liver, or bleeding problems
  • Can't switch easily between capsules, tablets, and liquid (can't be substituted for one another)

Common Side Effects for Meloxicam

  • Headache
  • Diarrhea
  • Indigestion
  • Nausea
  • Stomach pain
  • Joint pain
  • Flu-like symptoms

Warnings for Meloxicam

  • Risk of stomach ulcers and stomach bleeding
  • Risk of heart attack and stroke
  • High blood pressure
  • Swelling and risk of heart failure
  • Liver problems
  • Kidney damage
  • High potassium levels
  • Risk of general bleeding and anemia
  • Severe allergic reactions and skin reactions
  • Worsening asthma in certain people
  • Harm to an unborn baby

Summary for Prednisone

Prescription only

Prednisone is an oral corticosteroid. It's taken by mouth by adults and children to treat health conditions related to an overactive immune system or inflammation, such as allergies and certain skin conditions. Your healthcare team will determine your dose based on what medical condition you have. Some of the common short-term side effects of prednisone include stomach irritation and mood changes. And if you take this medication for a month or longer, you're more likely to experience long-term side effects, like weight gain and weakened immune system.

Indications for Prednisone

This medication is used for many different conditions. Generally, it's used for autoimmune problems, conditions related to swelling, or cancer. Some examples include:

Pros and Cons for Prednisone

Pros

  • Works well to treat many different conditions involving the immune system
  • Available as a liquid, which is a good option for people who have difficulty swallowing pills
  • Available as a lower-cost generic
  • Dose can be adjusted based on your response to the medication

Cons

  • Can cause side effects like upset stomach, mood changes, and sleep problems
  • Need to taper your dose before stopping (if you took it for more than a couple of weeks)
  • Might raise your risk for infections, bone weakening, and skin problems if used long term
  • Can slow growth in children if they take it for a long period of time

Common Side Effects for Prednisone

  • Swelling (e.g., puffiness in the face, hands, or feet)
  • Stomach bloating
  • Muscle weakness
  • Headache
  • Insomnia (trouble sleeping)
  • Changes in your mood
  • Larger appetite (possibly leading to weight gain)
  • Higher blood sugar

Warnings for Prednisone

  • Greater risk of infections
  • Mood and behavior changes
  • Reduced adrenal gland function
  • Changes in heart and kidney function
  • Stomach problems
  • Bone problems with long-term use
  • Eye problems with long-term use

Prices with our coupons for Meloxicam vs. Prednisone

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Meloxicam30 tablets / 15mg
$9.84$12.84
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Prednisone10 tablets / 20mg
$8.95-
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