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Luvox vs. Prozac

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Fluvoxamine and Prozac (generic name: fluoxetine) are both selective serotonin reuptake inhibitors (SSRIs) but are used for different conditions. Fluvoxamine is primarily used to treat obsessive-compulsive disorder (OCD) and is available only in generic form. Prozac, on the other hand, is used to treat a wider range of conditions, including major depressive disorder (MDD), OCD, bulimia, panic disorder, depression from bipolar 1 disorder, and treatment-resistant depression. Fluvoxamine is typically taken once or twice daily, while Prozac can be taken daily or weekly, depending on the form. Both medications can cause side effects like nausea and sleep problems, but fluvoxamine is more likely to cause side effects such as diarrhea and has a higher risk of drug interactions. Prozac is less likely to cause weight gain compared to other SSRIs and is available in both brand and generic forms. Both medications require a prescription and should not be stopped suddenly to avoid withdrawal symptoms.

Fluvoxamine

 

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Fluoxetine

(Prozac)

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Summary for Luvox

Prescription only

Fluvoxamine maleate is an SSRI, or a selective serotonin reuptake inhibitor. It's approved to treat obsessive-compulsive disorder (OCD) in people ages 8 years and up. Fluvoxamine comes as immediate-release tablets taken by mouth once or twice a day. For adults, it also comes as extended-release capsules taken once a day. Your specific dosage depends on which form you're taking. Side effects include nausea, sleepiness or trouble sleeping, and headache. Fluvoxamine is a generic medication; the brand name Luvox is no longer available.

Indications for Luvox

Pros and Cons for Luvox

Pros

  • A first-choice treatment option for OCD
  • Immediate-release tablets approved for children as young as 8 years old

Cons

  • Can cause a lot of side effects, like sleepiness, nausea, diarrhea, and dry mouth
  • Can interact with many medications, such as triptan migraine medications, antidepressants, and benzodiazepines

Common Side Effects for Luvox

Immediate-release tablets:

  • Nausea (40%)
  • Headache (22%)
  • Sleepiness (22%)
  • Trouble sleeping (21%)
  • Dry mouth (14%)
  • Weakness (14%)
  • Nervousness (12%)
  • Dizziness (11%)
  • Diarrhea (11%)
  • Constipation (10%)
  • Indigestion (10%)

Extended-release capsules:

  • Trouble sleeping (35%)
  • Nausea (34%)
  • Headache (32%)
  • Sleepiness (27%)
  • Weakness (26%)
  • Diarrhea (18%)
  • Low appetite (13%)
  • Dizziness (12%)
  • General pain (10%)
  • Dry mouth (10%)
  • Low sex drive or ejaculation problems (10%)

Warnings for Luvox

  • Risk of suicidal thoughts and behavior
  • Serotonin syndrome
  • Dangerous drug interactions
  • Withdrawal symptoms
  • Higher risk of bleeding
  • Low sodium levels
  • Sexual problems
  • Not for use alone for bipolar disorder because of the risk of mania
  • Angle-closure glaucoma in certain people

Summary for Prozac

Prescription only

Fluoxetine (Prozac) is a selective serotonin reuptake inhibitor (SSRI). It's used to treat several mental health conditions, including depression and panic disorder. The immediate-release pill and liquid are taken by mouth, typically once or twice daily. The delayed-release capsule is taken weekly, but it's approved only for depression. Some common side effects of fluoxetine (Prozac) include headaches, difficulty sleeping, and tiredness. Don't suddenly stop this medication if you've been taking it for a while; doing so can lead to symptoms of withdrawal.

Indications for Prozac

Pros and Cons for Prozac

Pros

  • Good choice for treating depression, OCD, and panic disorder
  • Less likely to make you sleepy compared to some other antidepressants, such as paroxetine (Paxil)
  • Taken by mouth, typically once daily (IR capsules and liquid) or once weekly (DR capsules, for depression only)
  • Can be taken with or without food

Cons

  • Can take up to 2 months for you to feel the full effects of the medication
  • Can raise the risk of suicidal thoughts and/or behavior in those age 24 or younger
  • Can interact with other medications, especially those affecting serotonin levels
  • Can cause withdrawal symptoms if you suddenly stop taking it

Common Side Effects for Prozac

  • Difficulty falling asleep (up to 33%)
  • Nausea (up to 29%)
  • Headache (21%)
  • Weakness (up to 21%)
  • Diarrhea (up to 18%)
  • Low appetite (up to 17%)
  • Drowsiness (up to 17%)
  • Anxiety (up to 15%)
  • Nervousness (up to 14%)
  • Tremor (up to 13%)
  • Dry mouth (up to 12%)
  • Throat pain (up to 11%)
  • Yawning (up to 11%)
  • Low sex drive (up to 11%)

Warnings for Prozac

  • Worsening depression, suicidal thoughts and behavior
  • Anxiety and trouble sleeping
  • Serotonin syndrome
  • Severe allergic reactions
  • Not for use alone in bipolar disorder
  • Risk of bleeding
  • Glaucoma
  • Low blood sodium levels
  • Life-threatening abnormal heart rhythm (QT prolongation)

Prices with our coupons for Luvox vs. Prozac

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Fluvoxamine90 tablets / 100mg
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Fluoxetine30 tablets / 20mg
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