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Luvox vs. Effexor XR

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Fluvoxamine (Luvox) and venlafaxine (Effexor) are both medications used to treat mental health conditions, but they belong to different classes and have different uses. Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI) primarily used to treat obsessive-compulsive disorder and is available only in generic form. Venlafaxine, on the other hand, is a serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder, anxiety, social anxiety disorder, and panic disorder, and is available in both generic and brand forms. Fluvoxamine is typically taken once or twice daily, while venlafaxine can be taken once daily in its extended-release form or multiple times a day in its immediate-release form. Fluvoxamine is more likely to cause side effects like nausea and sleep problems, whereas venlafaxine can cause side effects such as nausea, tiredness, and dry mouth. Both medications can lead to withdrawal symptoms if stopped abruptly, but venlafaxine is known for having more severe withdrawal symptoms.

Fluvoxamine

 

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Venlafaxine

 

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Summary for Luvox

Prescription only

Fluvoxamine maleate is an SSRI, or a selective serotonin reuptake inhibitor. It's approved to treat obsessive-compulsive disorder (OCD) in people ages 8 years and up. Fluvoxamine comes as immediate-release tablets taken by mouth once or twice a day. For adults, it also comes as extended-release capsules taken once a day. Your specific dosage depends on which form you're taking. Side effects include nausea, sleepiness or trouble sleeping, and headache. Fluvoxamine is a generic medication; the brand name Luvox is no longer available.

Indications for Luvox

Pros and Cons for Luvox

Pros

  • A first-choice treatment option for OCD
  • Immediate-release tablets approved for children as young as 8 years old

Cons

  • Can cause a lot of side effects, like sleepiness, nausea, diarrhea, and dry mouth
  • Can interact with many medications, such as triptan migraine medications, antidepressants, and benzodiazepines

Common Side Effects for Luvox

Immediate-release tablets:

  • Nausea (40%)
  • Headache (22%)
  • Sleepiness (22%)
  • Trouble sleeping (21%)
  • Dry mouth (14%)
  • Weakness (14%)
  • Nervousness (12%)
  • Dizziness (11%)
  • Diarrhea (11%)
  • Constipation (10%)
  • Indigestion (10%)

Extended-release capsules:

  • Trouble sleeping (35%)
  • Nausea (34%)
  • Headache (32%)
  • Sleepiness (27%)
  • Weakness (26%)
  • Diarrhea (18%)
  • Low appetite (13%)
  • Dizziness (12%)
  • General pain (10%)
  • Dry mouth (10%)
  • Low sex drive or ejaculation problems (10%)

Warnings for Luvox

  • Risk of suicidal thoughts and behavior
  • Serotonin syndrome
  • Dangerous drug interactions
  • Withdrawal symptoms
  • Higher risk of bleeding
  • Low sodium levels
  • Sexual problems
  • Not for use alone for bipolar disorder because of the risk of mania
  • Angle-closure glaucoma in certain people

Summary for Effexor XR

Prescription only

Venlafaxine is an antidepressant used to treat mental health conditions like depression, generalized anxiety disorder, social anxiety disorder, and panic disorder. It comes in two forms: extended-release, which is taken once a day, and immediate-release, which is taken in split doses throughout the day. This medication can interact with many things, including other medications and alcohol. Possible side effects can include nausea, weight changes, and sexual problems. It can also cause withdrawal symptoms if you stop taking it suddenly.

Indications for Effexor XR

Pros and Cons for Effexor XR

Pros

  • Can treat multiple mental health conditions
  • Affects two chemicals in the brain that impact your mood
  • Lower risk of weight gain compared to other antidepressants
  • Comes in both immediate-release and extended-release versions

Cons

  • Might raise your blood pressure, especially at higher doses
  • Interacts with many medications
  • Can take up to 4 to 8 weeks before you feel the full effect
  • High risk of causing withdrawal symptoms if suddenly stopped

Common Side Effects for Effexor XR

Extended-release:

  • Nausea (29-31%)
  • Trouble sleeping (17-23%)
  • Dizziness (16-20%)
  • Loss of appetite (10-20%)
  • Drowsiness (15-17%)
  • Dry mouth (12-17%)
  • Abnormal ejaculation (10-16%)
  • Sweating (11-14%)
  • Weakness (8-13%)

Immediate-release:

  • Nausea (37%)
  • Headache (25%)
  • Drowsiness (23%)
  • Dry mouth (22%)
  • Dizziness (19%)
  • Trouble sleeping (18%)
  • Constipation (15%)
  • Nervousness (13%)
  • Weakness (12%)
  • Sweating (12%)
  • Abnormal ejaculation (12%)
  • Loss of appetite (11%)

Warnings for Effexor XR

  • Suicidal thoughts and behavior
  • Serotonin syndrome
  • High blood pressure
  • Higher bleeding risk
  • Mania
  • Glaucoma
  • Withdrawal
  • Seizures
  • Low sodium levels
  • Lung problems and pneumonia
  • Sexual problems

Prices with our coupons for Luvox vs. Effexor XR

Price Card Drug Icon
Fluvoxamine90 tablets / 100mg
$36.00$121.21
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Venlafaxine30 tablets / 75mg
$8.60$8.60
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