Skip to main content

Compare
Lodine vs. Celebrex

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Etodolac (formerly known as Lodine) and Celecoxib (Celebrex) are prescription non-steroidal anti-inflammatory drugs (NSAIDs). Both are used to treat pain and inflammation, however, they have several differences between them. Etodolac is available only as a generic and comes in immediate-release and extended-release forms. Celecoxib is available as both a brand (Celebrex) and a lower-cost generic. Etodolac can cause stomach issues and is not recommended for people with certain health conditions. Unlike etodolac, celecoxib has fewer stomach problems and is also used to treat a wider range of conditions, including ankylosing spondylitis and menstrual cramps. Children as young as 2 years old can take celecoxib for certain conditions, while the extended-release form of etodolac is safe for children who are at least 6 years of age. Both medications carry risks of heart attack, stroke, and stomach bleeding, but Celecoxib has a lower risk of causing stomach ulcers. You should avoid alcohol with both medications to reduce the risk of stomach bleeding.

Etodolac

 

Get free coupons

Celebrex

(celecoxib)

Get free coupons

Summary for Lodine

Prescription only

Etodolac, also known by its brand name Lodine, is a non-steroidal anti-inflammatory drug (NSAID). The immediate-release pills are taken throughout the day; they're approved for adults with sudden, short-term pain; rheumatoid arthritis; or osteoarthritis. There's also an extended-release tablet for people ages 6 years and older that's taken once per day for the same types of arthritis. Side effects can include stomach pain, dizziness, and rash. Etodolac is currently available by prescription as generic only; the brand name has been discontinued.

Indications for Lodine

Pros and Cons for Lodine

Pros

  • Works well to treat pain and inflammation
  • Extended-release tablets can be used for children as young as 6 years old
  • Available as a lower-cost generic

Cons

  • Only available as pills that can't be split, open, or crushed
  • Not safe to take after 20 weeks of pregnancy
  • Might not be the best option if you're 65 years or older or if you have kidney, heart, liver, or bleeding problems

Common Side Effects for Lodine

The following side effects were reported in 1% to 10% of people who took etodolac:

Warnings for Lodine

  • Stomach bleeding
  • Heart attack and stroke
  • High blood pressure and heart failure
  • Kidney damage
  • Liver problems
  • Severe allergic reactions and skin reactions
  • Not safe to take while pregnant
  • Risk for bleeding

Summary for Celebrex

Prescription only

Celecoxib, also known by the brand name Celebrex, is a prescription pain medication that's used to temporarily relieve aches and pains from certain conditions, such as different types of arthritis. Celebrex (celecoxib) is a non-steroidal anti-inflammatory drug (NSAID), but it has a lower risk of causing stomach upset than other medications in its drug class, such as naproxen. The dosage for Celebrex (celecoxib) is typically once or twice a day. It's recommended to avoid taking this medication with alcohol since it can raise your risk for stomach bleeding. Other side effects include headache, indigestion, and diarrhea.

Indications for Celebrex

Pros and Cons for Celebrex

Pros

  • Can use for different types of arthritis
  • Fewer stomach side effects compared to some other NSAIDs
  • Safe to take for children 2 years and older with RA
  • Can open capsules and mix contents with applesauce, so it's convenient for people with difficulty swallowing pills

Cons

  • Can raise the risk of heart attack and stroke
  • Not recommended during second and third trimesters of pregnancy
  • Not recommended for use if you have severe liver disease
  • Might not be safe for people with a sulfa allergy

Common Side Effects for Celebrex

Adults

Children

  • Headache (13%)
  • Fever (8%)
  • Belly pain (4-8%)
  • Cough (7%)
  • Nausea (7%)
  • Diarrhea (5%)
  • Common cold (stuffy nose, sneezing; 5%)

Warnings for Celebrex

  • Heart attack and stroke
  • Stomach bleeding and ulcers
  • Liver problems
  • High blood pressure and heart failure
  • Kidney damage and high potassium levels
  • Severe allergic reactions
  • Severe asthma attack
  • Harm to unborn babies

Prices with our coupons for Lodine vs. Celebrex

Price Card Drug Icon
Etodolac60 tablets / 400mg
--
Get free coupons
More Information
Price Card Drug Icon
Celecoxib30 capsules / 200mg
--
Get free coupons
More Information

Compare other Rheumatoid Arthritis and Osteoarthritis drugs

Ibuprofen vs. LodineLodine vs. Acetaminophen-with-codeineLodine vs. ArthrotecLodine vs. CelebrexLodine vs. Coumadin
Lodine vs. DiclofenacLodine vs. PlavixArthrotec vs. IbuprofenAspirin vs. IbuprofenDuexis vs. IbuprofenFentanyl vs. Acetaminophen-with-codeineIbuprofen vs. Acetaminophen-with-codeineIbuprofen vs. CelebrexIbuprofen vs. ClaritinIbuprofen vs. CoumadinIbuprofen vs. DayquilIbuprofen vs. DiclofenacIbuprofen vs. IndocinIbuprofen vs. MeloxicamIbuprofen vs. MobicIbuprofen vs. NaproxenIbuprofen vs. NorcoIbuprofen vs. PercocetIbuprofen vs. PlavixIbuprofen vs. VicoprofenIbuprofen vs. VoltarenMeloxicam vs. Acetaminophen-with-codeineMorphine-sulfate vs. Acetaminophen-with-codeineNaproxen vs. Acetaminophen-with-codeineRelafen vs. Ibuprofen

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.