Skip to main content
Drug bottle and Pill

Compare MS Contin vs. Tylenol With Codeine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Morphine (morphine sulfate) and Tylenol with Codeine (acetaminophen/codeine) are both used to relieve pain, but they have some key differences. Morphine is a stronger opioid medication that can be used for both sudden (acute) and long-lasting (chronic) pain. It comes in various forms, including pills, liquid, and suppositories, and is typically prescribed when non-opioid medications aren't enough. On the other hand, Tylenol with Codeine is a combination of acetaminophen and codeine, used for mild-to-moderate pain. It is available as a tablet and liquid and is generally for short-term use. Morphine is a Schedule II controlled substance, indicating a higher potential for misuse and dependence compared to Tylenol with Codeine, which is a Schedule III controlled substance. Both medications can cause side effects like sleepiness, dizziness, and constipation, but morphine has a higher risk of causing severe breathing problems and addiction. Additionally, Tylenol with Codeine contains acetaminophen, so you need to be cautious about not exceeding the daily limit to avoid liver damage.

drug combination

See more from our pharmacists

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.