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Lisinopril vs. Atenolol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lisinopril (Zestril) and atenolol (Tenormin) are both used to treat high blood pressure and to lower the risk of death after a heart attack, but they belong to different classes of medications and work in different ways. Lisinopril is an ACE inhibitor that relaxes blood vessels by blocking a protein called ACE, while Atenolol is a beta-blocker that slows down the heart rate, making it easier for the heart to pump blood. Lisinopril is also used to treat heart failure, whereas Atenolol is used to treat chest pain (angina). Lisinopril is available as a tablet and a liquid, making it a good option for people who have trouble swallowing pills, while Atenolol is only available as a tablet. Common side effects of Lisinopril include cough, dizziness, and headache, whereas Atenolol can cause tiredness, dizziness, and cold hands and feet. Both medications are not recommended during pregnancy or breastfeeding.

Lisinopril

(Zestril)

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Atenolol

(Tenormin)

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Summary for Lisinopril

Prescription only

Lisinopril (Zestril) is an angiotensin-converting enzyme inhibitor, or ACE inhibitor. It's used to treat high blood pressure in people 6 years and older. In adults, it's also approved to manage heart failure and to lower the risk of death after a heart attack. Lisinopril (Zestril) comes as a tablet that's taken by mouth once daily. There's also an oral solution available under the brand name Qbrelis. Some side effects include dizziness, cough, and headache.

Indications for Lisinopril

Pros and Cons for Lisinopril

Pros

  • Taken by mouth once per day
  • A first-choice medication for high blood pressure
  • Also helpful for heart failure and after a heart attack
  • Okay for children as young as 6 years old to take to treat high blood pressure

Cons

Common Side Effects for Lisinopril

  • Dizziness (up to 19%)
  • Low blood pressure (up to 11%)
  • Higher creatinine levels (up to 10%)

Warnings for Lisinopril

  • Harm to an unborn baby
  • Angioedema (swelling)
  • Low blood pressure
  • Possible worsening of kidney problems
  • High potassium levels
  • Liver problems

Summary for Atenolol

Prescription only

Atenolol (Tenormin) is a cardioselective beta-blocker that's used to treat high blood pressure and chest pain. It's also used to lower the risk of death after a heart attack. Atenolol (Tenormin) works by slowing down heart rate and making it easier for your heart to pump blood. Atenolol (Tenormin) is taken by mouth, typically once daily. Some common side effects of this medication include dizziness, feeling tired, and having cold hands and feet.

Indications for Atenolol

Pros and Cons for Atenolol

Pros

Cons

Common Side Effects for Atenolol

  • Feeling tired (up to 26%)
  • Dizziness (up to 13%)
  • Cold hands and feet (up to 12%)
  • Feeling depressed (up to 12%)
  • Trouble catching your breath (up to 6%)

Note: Side effects were reported by people who took atenolol for high blood pressure

Warnings for Atenolol

  • Worsening chest pain, heart attacks, and irregular heartbeat
  • Heart failure
  • Risk of difficulty breathing
  • Greater risk during surgery
  • Hiding symptoms of low blood sugar
  • Hiding symptoms of overactive thyroid
  • Risk of heart block (medication interaction)
  • Risk of harm to unborn and breastfed babies

Prices with our coupons for Lisinopril vs. Atenolol

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Lisinopril30 tablets / 20mg
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Atenolol30 tablets / 25mg
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