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Latuda vs. Geodon

Latuda, also known by its generic name lurasidone, is a type of atypical antipsychotic. It's used to treat schizophrenia in adults and teens. It can also help with depression from bipolar disorder in people 10 years and older. Latuda (lurasidone) comes as a tablet that you swallow whole once a day with food (at least 350 calories). The most common side effect is sleepiness. This medication isn't likely to cause weight gain. Latuda (lurasidone) is available as brand-name and generic versions.

• Schizophrenia in people 13 years and older
• Depression from bipolar 1 disorder in people 10 years and older
• Depression from bipolar 1 disorder in adults - as add-on therapy to lithium or divalproex (Depakote)

• Sleepiness
• Nausea
• Movement problems (e.g., tremors, slow movement, stiff muscles)
• Can't stay still (restlessness)

• Risk of suicidal thoughts and behavior
• Higher risk of death in older people with dementia-related psychosis
• Neuroleptic malignant syndrome (NMS)
• Trouble controlling muscle movements (tardive dyskinesia)
• Changes in blood sugar levels, cholesterol, and weight
• Low blood pressure and risk of falls
• Trouble concentrating and extreme sleepiness
• High prolactin levels
• Lower white blood cell count (leading to possible risk of infection)
• Seizures
• Risk of manic episode
• Higher risk of side effects in people with Parkinson's disease or Lewy body dementia

Ziprasidone (Geodon) is an atypical antipsychotic medication used to treat bipolar I disorder and schizophrenia in adults. It works by balancing the levels of certain chemicals in the brain, like dopamine and serotonin. Ziprasidone (Geodon) is taken by mouth, typically twice daily. It's also available as an injection that's given into the muscles by a healthcare provider to treat agitation in schizophrenia. Some common side effects of ziprasidone (Geodon) include uncontrolled body movements, sleepiness, and nausea.

• Bipolar I disorder
• Schizophrenia

• Uncontrolled body movements (14%)
• Sleepiness (14%)
• Nausea (10%)
• Constipation (9%)
• Indigestion (8%)
• Restlessness (8%)
• Dizziness (8%)
• Respiratory tract infection (8%)

Note: Side effects listed were reported by people who took ziprasidone for schizophrenia in a clinical study

• Higher risk of death in older adults with dementia-related psychosis
• Risk of suicidal thoughts and behavior
• Difficulty controlling muscle movements (tardive dyskinesia)
• Weight gain, higher blood sugar, and higher cholesterol levels
• Neuroleptic malignant syndrome
• Difficulty concentrating and extreme sleepiness
• Changes in blood pressure and higher risk of falls
• Risk of infection (from low white blood cell count)
• Seizures
• Serious skin reaction
• Prolonged and painful erection
• High prolactin levels
• Heart rhythm problems