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Incruse Ellipta vs. Breo Ellipta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Incruse Ellipta (umeclidinium) and Breo Ellipta (fluticasone/vilanterol) are both inhalers used for the maintenance treatment of chronic obstructive pulmonary disease (COPD), but they have some key differences. Incruse Ellipta is a long-acting muscarinic antagonist (LAMA) that works by relaxing the muscles in your airways. Breo Ellipta, on the other hand, combines an inhaled corticosteroid (ICS) and a long-acting beta agonist (LABA) to reduce inflammation and relax airway muscles. Incruse Ellipta is only available as a brand-name medication, whereas Breo Ellipta has a lower-cost generic option. Incruse Ellipta is not approved for asthma, but Breo Ellipta is approved for both COPD and asthma in adults and children. Common side effects of Incruse Ellipta include cold symptoms and cough, while Breo Ellipta can cause upper respiratory infections, sore throat, and headache. Additionally, Breo Ellipta requires you to rinse your mouth after use to prevent fungal infections, a step not needed with Incruse Ellipta.

Incruse Ellipta

(umeclidinium)

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Breo Ellipta

(fluticasone furoate / vilanterol)

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Summary for Incruse Ellipta

Prescription only

Incruse Ellipta (umeclidinium) is an long-acting muscarinic antagonist (LAMA). It's an inhaler used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. Incruse Ellipta (umeclidinium) is inhaled through the mouth once per day. People who use Incruse Ellipta (umeclidinium) typically don't experience too many side effects, but ones reported include common cold symptoms, like sore throat and cough.

Indications for Incruse Ellipta

Pros and Cons for Incruse Ellipta

Pros

  • Inhaled once per day
  • Might be easier to use compared to some other dry powder inhalers
  • Can be stored at room temperature

Cons

  • Can't use if you're severely allergic to milk proteins because it contains lactose
  • Not a rescue inhaler for sudden breathing problems
  • Brand-name medication only

Common Side Effects for Incruse Ellipta

Warnings for Incruse Ellipta

  • Not a rescue inhaler
  • Narrowing of your airways (bronchospasm)
  • Serious allergic reactions
  • Worsening narrow-angle glaucoma
  • Trouble urinating

Summary for Breo Ellipta

Prescription only

Breo Ellipta (fluticasone furoate / vilanterol) is a maintenance inhaler used every day to help manage asthma and chronic obstructive pulmonary disease (COPD). It's a combination of two medications: fluticasone, a corticosteroid that reduces swelling in your lungs, and vilanterol, a long-acting beta agonist (LABA) that helps relax your airways. The typical dose is one puff by mouth once a day. Breo Ellipta (fluticasone furoate / vilanterol) isn't for sudden breathing problems or asthma attacks. Side effects include oral thrush, sore throat, and headache.

Indications for Breo Ellipta

Pros and Cons for Breo Ellipta

Pros

  • Long-term treatment for both COPD and asthma
  • Inhaled only once a day
  • Might be easier to use compared to some other dry powder inhalers
  • Safe for children 5 years and older for asthma

Cons

  • Won't work well for asthma attacks or COPD flare ups
  • Not safe for those severely allergic to milk proteins since it contains lactose
  • Can cause thrush in mouth or throat
  • No need to prime or shake the inhaler before use

Common Side Effects for Breo Ellipta

Asthma (adults):

  • Common cold symptoms (7-10%)
  • Headache (5-8%)

Asthma (children):

  • Common cold symptoms (10%)
  • Upper respiratory tract infection (7%)

COPD:

  • Common cold symptoms (9%)
  • Upper respiratory tract infection (7%)
  • Headache (7%)
  • Oral thrush (5%)

Warnings for Breo Ellipta

  • Worsening asthma or COPD
  • Overdose
  • Oral thrush
  • Pneumonia
  • Higher risk of infection
  • Changes in stress hormone levels
  • Sudden narrowing of the airways
  • Serious allergic reactions
  • Heart problems
  • Risk of bone loss
  • Slowed growth in children
  • Eye problems
  • High blood sugar and low potassium

Prices with our coupons for Incruse Ellipta vs. Breo Ellipta

Price Card Drug Icon
Umeclidinium Ellipta30 inhalers / 30 blisters of 62.5mcg
$210.90$348.61
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Price Card Drug Icon
Fluticasone Furoate/Vilanterol Ellipta1 inhaler / 60 blisters of 100mcg/25mcg
$228.01$415.96
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