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Gentamicin vs. Tobrex

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Gentak (gentamicin) and Tobrex (tobramycin) are both aminoglycoside antibiotics used to treat bacterial infections of the eye or eyelid. Both medications are available as an eye drop and an eye ointment. Both medications require a prescription and are not available over-the-counter. Gentak and Tobrex work by blocking bacteria from making proteins necessary for their protective covering. However, Gentak is noted for its affordability and availability in a lower-cost generic in both forms, while Tobrex only has a generic solution. Tobrex is suitable for people as young as 2 months old. Common side effects for both include temporary eye irritation, but Tobrex may also cause eyelid itching and swelling. Both medications should be used for the full prescribed duration to prevent the infection from returning or becoming harder to treat.

Gentamicin

 

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Tobramycin

(Tobrex)

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Summary for Gentamicin

Prescription only

Gentamicin is a topical antibiotic that treats bacterial skin infections, such as impetigo. It comes as a cream that's useful for wet, oozing, or greasy skin infections. There's also a topical ointment for infections on dry skin. Both forms are applied on the skin 3 to 4 times a day. Gentamicin can be used on adults and children over 1 year of age. Most people don't have many side effects when used as directed. But it's possible to have mild skin irritation, like redness and itching.

Indications for Gentamicin

  • Impetigo
  • Other bacterial skin infections

Pros and Cons for Gentamicin

Pros

  • Treats various bacterial skin infections, including severe acne or impetigo
  • Very few side effects, so it's safe for most people if used as directed
  • Might be a good option for people who are sensitive to Neosporin

Cons

  • Applied many times a day
  • Can cause temporary skin irritation
  • Need a prescription from a healthcare professional

Common Side Effects for Gentamicin

  • Side effects aren't common. See "Other Side Effects."

Warnings for Gentamicin

  • Risk of other skin infections
  • Allergic reaction

Summary for Tobrex

Prescription only

Tobramycin (Tobrex) is an antibiotic that's used to treat different types of bacterial eye infections. It can be used for people ages 2 months and older. Tobramycin (Tobrex) comes as an ophthalmic solution (eye drops) and eye ointment that are used multiple times per day. It's available in both brand-name and generic versions. The most common side effects include eyelid itching, eyelid swelling, and eye redness. Like with all antibiotics, you shouldn't stop treatment too early because your infection could come back or get harder to treat.

Indications for Tobrex

  • Bacterial infections of the eye or eyelid

Pros and Cons for Tobrex

Pros

  • Treats various bacterial eye and eyelid infections
  • Ointment form requires fewer doses per day than most alternatives
  • Eye drop form is available as a lower-cost generic

Cons

  • Can cause temporary eye irritation
  • Might require more frequent dosing throughout the day for severe infections
  • Ointment form tends to be messy and harder to put in the eye

Common Side Effects for Tobrex

See Risks and Warnings.

Warnings for Tobrex

  • New infection
  • Allergic reaction
  • Avoid contact lenses
  • Slower healing (for eye ointment only)
  • Risk of contamination (spreading germs)

Prices with our coupons for Gentamicin vs. Tobrex

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Gentamicin2 tubes / 15g of 0.1%
$31.50$99.97
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Price Card Drug Icon
Tobramycin1 eye dropper / 5ml of 0.3%
$8.97$23.98
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