Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Gentak (gentamicin) and Ocuflox (ofloxacin) are both prescription antibiotics used to treat bacterial eye infections, but they belong to different classes of antibiotics. Gentak is an aminoglycoside antibiotic that works by blocking bacteria from making proteins necessary for their protective covering, while Ocuflox is a fluoroquinolone antibiotic that kills bacteria by blocking proteins they need to grow and repair their DNA. Gentak is available as both eye drops and an eye ointment, whereas Ocuflox is only available as eye drops. Gentak is typically used 2 to 3 times a day for eye ointment and every 4 hours for eye drops, while Ocuflox has a more frequent dosing schedule, especially for corneal ulcers, which may require application every 30 minutes initially. Common side effects of Gentak include temporary eye irritation or burning, while Ocuflox can cause a temporary burning sensation or discomfort in the eye. Both medications require you to follow specific instructions to avoid contamination and ensure effectiveness.
Gentamicin (Gentak)
Ofloxacin (Ocuflox)
Gentamicin (Gentak)
Ofloxacin (Ocuflox)
Summary of Gentamicin vs. Ocuflox
Summary for Aminoglycoside antibiotic
Prescription only
Gentamicin (Gentak) is a popular, affordable antibiotic for treating different types of bacterial eye infections. It comes as an eye drop and an eye ointment.
Summary for Fluoroquinolone antibiotic
Prescription only
Ofloxacin (Ocuflox) is an eye drop medication that's approved for use in people ages 1 year and older. It's a fluoroquinolone antibiotic that treats conjunctivitis (pink eye) and corneal ulcers caused by bacterial infections. Ofloxacin (Ocuflox) is typically used multiple times per day, depending on the reason you need the eye drops and what day of treatment you're on. Side effects aren't common but can include a temporary burning sensation or discomfort in the eye.