Compare Blephamide vs. Gentamicin

Blephamide (sulfacetamide/prednisolone) and Gentak (gentamicin) are both prescription eye medications used to treat bacterial eye infections, but they have some key differences. Blephamide is a combination of an antibiotic (sulfacetamide) and a corticosteroid (prednisolone), which means it not only fights bacteria but also reduces inflammation and pain. In contrast, Gentak contains only gentamicin, an aminoglycoside antibiotic, and does not have anti-inflammatory properties. Blephamide is available as an eye drop, while Gentak comes as an eye ointment and eye drops. Blephamide needs to be used multiple times a day, including at night, whereas Gentak's ointment form requires fewer doses per day. Additionally, Blephamide can cause high eye pressure and eye injury if used for a long time, which are not expected with Gentak. Both medications can lead to new infections if used for too long, but Blephamide also carries a risk of allergic reactions in people with sulfa allergies.