Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Moxifloxacin (Vigamox) and Ciprofloxacin (Ciloxan) are both fluoroquinolone antibiotics used to treat bacterial conjunctivitis (pink eye). However, there are some key differences between them. Moxifloxacin (Vigamox) is available in both brand-name and generic forms and is typically used three times a day for seven days. In contrast, Ciprofloxacin (Ciloxan) is available as a generic solution but its ointment form is brand-name only. Ciprofloxacin (Ciloxan) also treats corneal ulcers, requiring a more frequent dosing schedule, especially in the initial days of treatment. While both medications can cause eye irritation, Moxifloxacin (Vigamox) side effects include dry eye and blurry vision, whereas Ciprofloxacin (Ciloxan) can cause a white substance to form on corneal ulcers and a bad taste right after use. Both medications should not be used with contact lenses during treatment.
Moxifloxacin (Vigamox)
Ciprofloxacin (Ciloxan)
Moxifloxacin (Vigamox)
Ciprofloxacin (Ciloxan)
Summary of Vigamox vs. Ciloxan
Summary for Fluoroquinolone antibiotic
Prescription only
Moxifloxacin (Vigamox) is a fluoroquinolone antibiotic that treats bacterial conjunctivitis (pink eye) in people of all ages. It's an eye drop that's placed in the affected eye(s) 3 times per day for 7 days. Side effects aren't common but can include dry eye, eye pain, eye redness, and itchy eyes. This medication is available as a brand-name and generic version.
Summary for Fluoroquinolone antibiotic
Prescription only
Ciprofloxacin (Ciloxan) is an eye drop and eye ointment that can treat bacterial conjunctivitis (pink eye). The eye drops can also help treat corneal ulcers. This medication belongs to the drug class called fluoroquinolone antibiotics. Although the ciprofloxacin (Ciloxan) eye drops can be used for people of all ages, the eye ointment is approved for people who are 2 years old and older. The typical dosing varies greatly depending on the eye condition you have, what day of treatment you're on, and which formulation you're using. Side effects are often temporary; they can include eye discomfort, an aftertaste in the mouth, and itchy eye.