Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Ciprodex (ciprofloxacin/dexamethasone) and Otovel (ciprofloxacin/fluocinolone) are both ear drop medications used to treat ear infections in children aged 6 months and older. Ciprodex can treat both middle ear infections with ear tubes and outer ear infections (swimmer's ear), while Otovel is only for middle ear infections with ear tubes. Ciprodex combines ciprofloxacin, an antibiotic, with dexamethasone, a corticosteroid, whereas Otovel combines ciprofloxacin with fluocinolone, another corticosteroid. Ciprodex is available as a lower-cost generic, while Otovel comes in convenient, single-use vials but can be more expensive. Both medications need to be warmed in your hands before use to prevent dizziness and are used twice a day for 7 days. Common side effects for Ciprodex include ear discomfort and pain, while Otovel commonly causes ear drainage. Both medications carry risks of serious allergic reactions and should not be used for viral or fungal ear infections.
Summary for Fluoroquinolone antibiotic / Corticosteroid
Prescription only
Ciprodex is an ear drop suspension that contains ciprofloxacin (a fluoroquinolone antibiotic) and dexamethasone (a corticosteroid). It's used to treat middle and outer ear infections in people ages 6 years and older. The dosage is 4 drops twice a day, typically for 7 days. Side effects aren't common, but include ear discomfort, ear pain, and changes in taste. It's available as both a brand name (Ciprodex) and generic.
Summary for Fluoroquinolone antibiotic / Corticosteroid
Prescription only
Otovel (ciprofloxacin / fluocinolone) is a combination antibiotic and steroid medication that treats ear infections in children aged 6 months and older with surgically placed ear tubes (tympanostomy tubes). It's an ear drop that comes in convenient, single-use vials.
Indications of Ciprodex vs. Otovel
Indications for
•Middle ear infections (otitis media) in children ages 6 months and older with surgically-placed ear tubes (tympanostomy tubes)
•Outer ear canal infections (swimmer's ear or otitis externa) in people 6 months and older
Indications for
•Middle ear infections in children with ear tubes
Pros and Cons of Ciprodex vs. Otovel
Pros and Const for Fluoroquinolone antibiotic / Corticosteroid