Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Moxifloxacin (Vigamox) and tobramycin (Tobrex) are both antibiotics used to treat bacterial eye infections, but they belong to different classes. Moxifloxacin is a fluoroquinolone antibiotic, while tobramycin is an aminoglycoside antibiotic. Moxifloxacin is typically used for bacterial conjunctivitis (pink eye) and is applied as eye drops three times a day for seven days. Tobramycin, on the other hand, treats various bacterial eye and eyelid infections and is available as both eye drops and ointment. The dosing for tobramycin varies based on the severity of the infection, with more frequent applications for severe cases. Common side effects of both medications include eye itching, swelling, and redness. Both medications are available in generic forms and should be used for the full prescribed duration to prevent the infection from returning.
Moxifloxacin (Vigamox)
Tobramycin (Tobrex)
Moxifloxacin (Vigamox)
Tobramycin (Tobrex)
Summary of Vigamox vs. Tobrex
Summary for Fluoroquinolone antibiotic
Prescription only
Moxifloxacin (Vigamox) is a fluoroquinolone antibiotic that treats bacterial conjunctivitis (pink eye) in people of all ages. It's an eye drop that's placed in the affected eye(s) 3 times per day for 7 days. Side effects aren't common but can include dry eye, eye pain, eye redness, and itchy eyes. This medication is available as a brand-name and generic version.
Summary for Aminoglycoside antibiotic
Prescription only
Tobramycin (Tobrex) is an antibiotic that's used to treat different types of bacterial eye infections. It can be used for people ages 2 months and older. Tobramycin (Tobrex) comes as an ophthalmic solution (eye drops) and eye ointment that are used multiple times per day. It's available in both brand-name and generic versions. The most common side effects include eyelid itching, eyelid swelling, and eye redness. Like with all antibiotics, you shouldn't stop treatment too early because your infection could come back or get harder to treat.