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Tobrex vs. Besivance

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Tobrex (tobramycin) and Besivance (besifloxacin) are both prescription eye drops used to treat bacterial eye infections, but they belong to different classes of antibiotics. Tobrex is an aminoglycoside antibiotic available in both brand-name and generic forms, while Besivance is a fluoroquinolone antibiotic and is only available as a brand-name medication. Tobrex can be used for people as young as 2 months old and comes in both eye drop and ointment forms, whereas Besivance is approved for use in children 1 year and older and is only available as eye drops. Tobrex is typically used multiple times per day, with the frequency depending on the severity of the infection, while Besivance is used three times per day for 7 days. Common side effects of Tobrex include eyelid itching, swelling, and eye redness, whereas Besivance may cause temporary eye redness or irritation. Both medications should be used for the full prescribed duration to prevent the infection from returning or becoming harder to treat.

Tobramycin

(Tobrex)

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Besivance

(besifloxacin)

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Summary for Tobrex

Prescription only

Tobramycin (Tobrex) is an antibiotic that's used to treat different types of bacterial eye infections. It can be used for people ages 2 months and older. Tobramycin (Tobrex) comes as an ophthalmic solution (eye drops) and eye ointment that are used multiple times per day. It's available in both brand-name and generic versions. The most common side effects include eyelid itching, eyelid swelling, and eye redness. Like with all antibiotics, you shouldn't stop treatment too early because your infection could come back or get harder to treat.

Indications for Tobrex

  • Bacterial infections of the eye or eyelid

Pros and Cons for Tobrex

Pros

  • Treats various bacterial eye and eyelid infections
  • Ointment form requires fewer doses per day than most alternatives
  • Eye drop form is available as a lower-cost generic

Cons

  • Can cause temporary eye irritation
  • Might require more frequent dosing throughout the day for severe infections
  • Ointment form tends to be messy and harder to put in the eye

Common Side Effects for Tobrex

See Risks and Warnings.

Warnings for Tobrex

  • New infection
  • Allergic reaction
  • Avoid contact lenses
  • Slower healing (for eye ointment only)
  • Risk of contamination (spreading germs)

Summary for Besivance

Prescription only

Besivance is a prescription eye drop used to treat bacterial pink eye in adults and children 1 year of age and older. It belongs to the fluoroquinolone antibiotic class. The dosage is typically 1 drop three times per day for 7 days to treat the eye infection. Currently it's available only as a brand-name medication as a generic is not yet available. Side effects aren't common, but include eye redness.

Indications for Besivance

  • Bacterial conjunctivitis (pink eye) in people ages 1 year and older

Pros and Cons for Besivance

Pros

  • Applied directly to the eye to target the infection
  • Side effects aren't common and are usually mild
  • Can be used in children as young as 1 year old

Cons

  • Can cause temporary eye redness or irritation
  • Can take days before you get symptom relief
  • No lower-cost generic is available

Common Side Effects for Besivance

  • Eye redness (2%)

Warnings for Besivance

  • Only for use on the surface of the eye
  • New or worsening eye infections

Prices with our coupons for Tobrex vs. Besivance

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Tobramycin1 eye dropper / 5ml of 0.3%
$8.97-
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Besivance1 eye dropper / 5ml of 0.6%
$140.05$227.22
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