Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Erythromycin (Ilotycin) and Tobramycin (Tobrex) are both antibiotics used to treat bacterial eye infections, but they belong to different classes. Erythromycin is a macrolide antibiotic, while Tobramycin is an aminoglycoside antibiotic. Erythromycin is typically used as an eye ointment and can be applied up to 6 times a day, whereas Tobramycin is available as both eye drops and ointment, with the drops used every 4 hours for mild infections and more frequently for severe ones. Erythromycin is often used to prevent pink eye in newborns, while Tobramycin is suitable for people aged 2 months and older. Common side effects of Erythromycin include mild eye irritation and redness, while Tobramycin can cause eyelid itching, swelling, and eye redness. Both medications should be used as directed by your healthcare provider to avoid the risk of new or worsened infections.
Erythromycin eye ointment
Tobramycin (Tobrex)
Erythromycin eye ointment
Tobramycin (Tobrex)
Summary of Ilotycin vs. Tobrex
Summary for Macrolide antibiotic
Prescription only
Erythromycin eye ointment is used to treat and prevent various bacterial eye infections, including pink eye in newborns. The typical dosage for this medication is to apply it in the affected eye(s) up to 6 times a day. Most people experience few to no side effects while using erythromycin eye ointment as directed.
Summary for Aminoglycoside antibiotic
Prescription only
Tobramycin (Tobrex) is an antibiotic that's used to treat different types of bacterial eye infections. It can be used for people ages 2 months and older. Tobramycin (Tobrex) comes as an ophthalmic solution (eye drops) and eye ointment that are used multiple times per day. It's available in both brand-name and generic versions. The most common side effects include eyelid itching, eyelid swelling, and eye redness. Like with all antibiotics, you shouldn't stop treatment too early because your infection could come back or get harder to treat.