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Compare Vigamox vs. Zylet

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Moxifloxacin (Vigamox) and Zylet (loteprednol/tobramycin) are both prescription eye medications, but they serve different purposes and belong to different drug classes. Moxifloxacin (Vigamox) is a fluoroquinolone antibiotic used to treat bacterial conjunctivitis (pink eye) and is available in both brand-name and generic forms. It works by blocking proteins that bacteria need to grow and survive. You need to use it three times a day for seven days. Common side effects include dry eye, eye pain, and redness. On the other hand, Zylet (loteprednol/tobramycin) is a combination of a corticosteroid and an antibiotic, used to treat or prevent eye inflammation and bacterial infections. It is only available as a brand-name medication. Zylet needs to be used more frequently, especially in the beginning, and can cause higher eye pressure and eye injury if used for too long. Common side effects include eye redness, cornea inflammation, and headaches. While both medications treat bacterial eye infections, Zylet also addresses inflammation, making it suitable for more complex eye conditions.

  • Moxifloxacin (Vigamox)
    Zylet (loteprednol / tobramycin)
  • Moxifloxacin (Vigamox)
    Zylet (loteprednol / tobramycin)

  • Summary of Vigamox vs. Zylet

    Summary for Fluoroquinolone antibiotic
    Prescription only

    Moxifloxacin (Vigamox) is a fluoroquinolone antibiotic that treats bacterial conjunctivitis (pink eye) in people of all ages. It's an eye drop that's placed in the affected eye(s) 3 times per day for 7 days. Side effects aren't common but can include dry eye, eye pain, eye redness, and itchy eyes. This medication is available as a brand-name and generic version.

    Summary for Corticosteroid / Antibiotic
    Prescription only

    Zylet is a combination eye drop medication that contains two active ingredients: loteprednol and tobramycin. It's approved for use in people 7 years and older to treat bacterial eye infections, like pink eye, and related eye redness and swelling (inflammation). The corticosteroid (or steroid), loteprednol, helps lessen eye inflammation and the aminoglycoside antibiotic, tobramycin, fights off bacteria causing the eye infection. Zylet eye drops are placed directly into the affected eye(s) every 4 to 6 hours. Side effects include eye irritation and headache.

  • Indications of Vigamox vs. Zylet

    Indications for
    •Bacterial conjunctivitis (pink eye)
    Indications for
    •Eye inflammation from a bacterial infection in the eye
    •Eye inflammation when there's a risk for a bacterial infection in the eye

  • Pros and Cons of Vigamox vs. Zylet

    Pros and Const for Fluoroquinolone antibiotic
    Pros
    •Can typically start to improve symptoms in a few days
    •Generally used less often during the day than alternatives
    •Safe to use in children and infants
    •Available as a lower-cost generic
    Cons
    •Need to use 3 times a day
    •Can cause eye discomfort
    •Might be difficult for some people to use properly
    Pros and Const for Corticosteroid / Antibiotic
    Pros
    •Relieves eye inflammation and treats the bacteria eye infection at the same time
    •Conveniently combines two medications into a single product
    •Applied directly to the eyes (where the inflammation and infection is)
    Cons
    •Need to use multiple times per day
    •Might be difficult for some people to use properly
    •Not available as a lower-cost generic; brand-name medication only

  • Common Side Effects of Vigamox vs. Zylet

    Common Side Effects for
    •Eye inflammation or redness (up to 6%)
    •Blurry vision (up to 6%)
    •Dry eye (up to 6%)
    •Eye irritation, pain, or itching (up to 6%)
    •Watery eye (up to 6%)
    Common Side Effects for
    •Redness and swelling of the cornea of the eye (15%)
    •Headache (14%)
    •Higher eye pressure (10%)
    •Burning and stinging sensation in the eye (9%)

  • Warnings of Vigamox vs. Zylet

    Common Side Effects for
    •For use in the eye only
    •Risk of developing new infection
    •Don't wear contact lenses
    •Severe allergic reaction
    Common Side Effects for
    •For use in the eye only
    •Eye infections and eye problems when used for a long time
    •Slow healing of the eye after an eye procedure
    •Possible eye injury or damage
    •Don't wear contact lenses
    •Allergic reaction

  • Prices with our coupons for Vigamox vs. Zylet

    Learn more about Moxifloxacin
    Learn more about Zylet

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