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Diethylpropion vs. Phendimetrazine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Diethylpropion

 

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Phendimetrazine

 

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Summary for Diethylpropion

Prescription only

Diethylpropion is a medication that's taken by mouth help with obesity and weight loss. It's typically used together with a low-calorie diet and exercise plan. This medication is only meant to be used for a short period of time because it has many potential risks.

Indications for Diethylpropion

  • Weight management when diet and exercise alone aren't enough in people with obesity

Pros and Cons for Diethylpropion

Pros

  • An option to help manage your weight when diet and exercise alone haven't worked
  • Helps lower your appetite so you're not as hungry before meals
  • Comes as both an immediate-release tablet (taken before each meal) and an extended-release tablet (taken once a day)
  • Lower-cost generic available

Cons

  • Might not be a good choice for people age 65 or older, or people with kidney or heart problems
  • Can cause withdrawal symptoms if you stop the medication after taking it for a while
  • Not for long-term use
  • Might not work as well as other weight loss medications
  • Not recommended for people who've taken similar weight loss medications (like phentermine (Adipex-P)) in the past year

Common Side Effects for Diethylpropion

  • Nausea
  • Vomiting
  • Diarrhea
  • Upset stomach
  • Constipation
  • Dry mouth
  • Headache
  • Nervousness
  • Jitteriness
  • Racing heart
  • Trouble falling asleep
  • Changes in sex drive

Warnings for Diethylpropion

  • High blood pressure affecting the heart and lungs
  • Heart valve problems
  • Potential for misuse and dependence

Summary for Phendimetrazine

Prescription only

Phendimetrazine, formerly known as brand-name medication Bontril, is a prescription sympathomimetic medication typically used in combination with diet and exercise. It works as an appetite suppressant in the brain to help adults with weight loss. It's available as an immediate-release tablet taken by mouth two to three times per day, and an extended-release capsule taken once per day. Side effects include restlessness, headache, and high blood pressure.

Indications for Phendimetrazine

Short-term treatment for weight management in adults with a body mass index (BMI) of:

Pros and Cons for Phendimetrazine

Pros

  • Comes in immediate-release and extended-release forms
  • Available as a lower-cost generic form

Cons

  • Risk of misuse and dependency
  • Typically recommended to be used for a short period of time (a few weeks)

Common Side Effects for Phendimetrazine

  • Fast heartbeat
  • High blood pressure
  • Restlessness
  • Trouble sleeping
  • Nervousness
  • Shakiness
  • Sweating

Warnings for Phendimetrazine

  • Not safe with other weight loss medications
  • Lower response to the medication over time
  • Risk of misuse and dependence
  • High blood pressure in the lungs (pulmonary hypertension)
  • Heart valve problem
  • Risk of high blood pressure
  • Risk of low blood sugar in people with diabetes

Prices with our coupons for Diethylpropion vs. Phendimetrazine

Price Card Drug Icon
Diethylpropion30 tablets / 75mg
$35.27$48.00
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Price Card Drug Icon
Phendimetrazine90 tablets / 35mg
$13.44$46.03
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