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Diclegis vs. Bonjesta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Diclegis

(doxylamine / pyridoxine)

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Bonjesta

(doxylamine / pyridoxine)

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Summary for Diclegis

Prescription only

Diclegis (doxylamine / pyridoxine) helps treat morning sickness, or nausea and vomiting that people experience during pregnancy. It's typically taken when changing your diet or avoiding nausea triggers isn't enough. This medication contains an antihistamine called doxylamine and a dietary supplement called pyridoxine (also known as vitamin B6). The dosage starts at 2 tablets taken by mouth at bedtime, but it can be adjusted if you need more relief. A common side effect is sleepiness. This medication has a brand-name and generic version.

Indications for Diclegis

  • Morning sickness (nausea and vomiting during pregnancy) when non-medication options haven't provided enough relief

Pros and Cons for Diclegis

Pros

  • One of the few medications that's FDA approved for morning sickness during pregnancy
  • Combines two medications into one tablet for convenience
  • Dose can be adjusted based on response

Cons

  • Dose ranges from 2 to 4 tablets per day, depending on your needs
  • Not for severe nausea and vomiting during pregnancy (hyperemesis gravidarum)
  • Not known whether it works well or is safe for people under 18 years old

Common Side Effects for Diclegis

  • Sleepiness (14%)

Warnings for Diclegis

  • Sleepiness
  • Worsening of certain other medical conditions

Summary for Bonjesta

Prescription only

Bonjesta (doxylamine / pyridoxine) treats morning sickness, or nausea and vomiting that happens during pregnancy. It's typically taken when changing your diet or staying away from nausea triggers isn't enough help. This medication contains an antihistamine called doxylamine and a dietary supplement called pyridoxine (also known as vitamin B6). The dosage is 1 tablet taken by mouth at bedtime, but it can be adjusted to 1 tablet in the morning and 1 tablet at bedtime if needed. This medication commonly causes sleepiness as a side effect.

Indications for Bonjesta

  • Morning sickness (nausea and vomiting during pregnancy) when non-medication options haven't provided enough relief

Pros and Cons for Bonjesta

Pros

  • One of the few medications that's FDA approved for morning sickness during pregnancy
  • Combines two medications into one tablet for convenience
  • Dose ranges from 1 to 2 tablets per day, depending on your needs

Cons

  • Can cause sleepiness
  • Not for severe nausea and vomiting during pregnancy (hyperemesis gravidarum)
  • Not known whether it works well or is safe for people under 18 years old

Common Side Effects for Bonjesta

  • Sleepiness (14%)

Warnings for Bonjesta

  • Sleepiness
  • Worsening of certain other medical conditions

Prices with our coupons for Diclegis vs. Bonjesta

Price Card Drug Icon
Doxylamine/Pyridoxine60 tablets / 10mg/10mg
$55.41$107.12
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Price Card Drug Icon
Bonjesta60 tablets / 20mg/20mg
$180.00$824.01
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