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Coreg vs. Zebeta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Carvedilol (Coreg) and bisoprolol (formerly branded as Zebeta) are both beta blockers used to treat high blood pressure, but they have some key differences. Carvedilol is also used to manage heart failure and reduce the risk of death after a heart attack, while bisoprolol is typically only used for high blood pressure when other medications aren't effective. Carvedilol comes in both immediate-release tablets taken twice daily and extended-release capsules taken once daily, whereas bisoprolol is taken once daily. Carvedilol is a non-selective beta blocker, affecting both the heart and blood vessels, while bisoprolol is cardioselective, primarily targeting the heart, which may make it less likely to cause breathing problems. Common side effects of carvedilol include dizziness and tiredness, while bisoprolol commonly causes headaches and fatigue. Both medications are available as lower-cost generics.

Carvedilol

(Coreg)

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Bisoprolol

 

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Summary for Coreg

Prescription only

Carvedilol (Coreg) is used to treat high blood pressure, manage heart failure, and help with heart problems after a heart attack. It belongs to the beta blocker drug class. This medication comes as a tablet that's taken by mouth twice daily, and as an oral extended-release (ER) capsule (brand name Coreg CR) that's taken once daily. Common side effects include dizziness, feeling tired, and diarrhea.

Indications for Coreg

  • High blood pressure
  • Heart failure
  • Lower the risk of death from heart-related problems after a heart attack

Pros and Cons for Coreg

Pros

  • Taken by mouth
  • Comes as a once-daily extended-release formulation
  • Dose can be adjusted based on your response
  • Available as a lower-cost generic

Cons

  • Need to take with food
  • Can cause you to feel more tired
  • Can cause dry eyes if you wear contact lenses
  • Shouldn't be taken if you have asthma or an asthma-related condition

Common Side Effects for Coreg

  • Dizziness (6%)

Please note: These side effects were reported by people who took carvedilol (Coreg) in clinical studies for high blood pressure.

Warnings for Coreg

  • Worsening chest pain and heart attacks
  • Slow heart rate and low blood pressure
  • Heart failure
  • Hiding symptoms of low blood sugar
  • Risk of difficulty breathing
  • Hiding symptoms of high thyroid hormone
  • Risk of kidney problems
  • Severe allergic reactions
  • Greater risk during surgery
  • Risk of eye problems during surgery

Summary for Zebeta

Prescription only

Bisoprolol, or bisoprolol fumarate, is a tablet that's used to treat high blood pressure. It belongs to a group of medications called beta blockers. It's usually only given when first-choice blood pressure medications aren't working well enough. Some common side effects of bisoprolol include headache, feeling tired, and diarrhea. It has some interactions with alcohol and taking bisoprolol with alcohol can worsen dizziness and raise the risk for fainting.

Indications for Zebeta

  • High blood pressure

Pros and Cons for Zebeta

Pros

  • Works well to lower blood pressure
  • Available as a lower-cost generic
  • Only need to take it once a day
  • Can take it with or without food

Cons

  • Not a first-choice medication to lower blood pressure
  • Skipping or missing doses can lead to high blood pressure and higher risk of heart attacks
  • Can make you feel more tired
  • Can hide symptoms of low blood sugar if you have diabetes

Common Side Effects for Zebeta

  • Headache (9%)
  • Fatigue (7%)
  • Upper respiratory tract infection (5%)
  • Swelling in arms or legs (4%)
  • Dizziness (3%)
  • Runny nose (3%)

Warnings for Zebeta

  • Heart attack or irregular heart rhythm
  • Heart failure
  • Trouble breathing (people with bronchospastic conditions)
  • Hiding symptoms of low blood sugar
  • Hiding symptoms of high thyroid hormone
  • Severe allergic reactions
  • Worsening of poor circulation

Prices with our coupons for Coreg vs. Zebeta

Price Card Drug Icon
Carvedilol180 tablets / 25mg
$22.74$115.48
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Bisoprolol30 tablets / 5mg
$9.00$9.00
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