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Capoten vs. Aceon

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Captopril (Capoten) and perindopril (Aceon) are both ACE inhibitor medications used to treat high blood pressure and certain heart-related conditions, including lowering the risk of heart attack. Captopril is taken two to three times a day on an empty stomach, while perindopril is usually taken once a day. Both medications are available as a lower-cost generic. Side effects of both medications include a dry cough and dizziness, and both may rarely cause angioedema. Both medications can interact with NSAIDs like ibuprofen (Motrin) and naproxen (Aleve) and are not recommended during pregnancy.

Captopril

 

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Perindopril

 

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Summary for Capoten

Prescription only

Captopril is an angiotensin-converting enzyme (ACE) inhibitor. It's used in adults to treat high blood pressure, heart failure, and to prevent the worsening of kidney problems in people who have diabetes. Captopril is available as a tablet that's taken by mouth two to three times per day. Your healthcare team will help determine your dose based on different factors, such as how high your blood pressure is and what other medications you're taking. Side effects include a dry cough, changes in taste, and dizziness. Brand name Capoten has been discontinued; captopril is only available as a generic medication.

Indications for Capoten

Pros and Cons for Capoten

Pros

  • A first-choice medication for lowering blood pressure for many people
  • Taken by mouth
  • Available as a lower-cost generic

Cons

  • Taken two to three times per day
  • Need to take on an empty stomach, 1 hour before meals
  • Can't take during pregnancy

Common Side Effects for Capoten

  • Skin rash (up to 7%)
  • Changes in taste (up to 4%)
  • Dry cough (up to 2%)
  • Itching (2%)

Warnings for Capoten

  • Not safe during pregnancy
  • Angioedema (swelling) and serious allergic reactions
  • Risk of infection (lower white blood cell count)
  • Low blood pressure
  • Worsening kidney problems
  • High potassium levels
  • Risk of liver problems

Summary for Aceon

Prescription only

Perindopril is a prescription medication that's used to treat high blood pressure. It's also used to lower the risk of death or heart attack in certain people with coronary artery disease (CAD). The dosage for perindopril can differ if you're older, have kidney problems, or are taking diuretics ("water pills"). Common side effects include dry cough, dizziness, and back pain. Although the brand name for this medication, Aceon, is discontinued, perindopril is available as a lower-cost, generic tablet.

Indications for Aceon

Pros and Cons for Aceon

Pros

  • Available as a lower-cost generic medication
  • Typically taken once a day
  • Lowers the risk of heart attack or death due to heart problems in people with CAD

Cons

Common Side Effects for Aceon

  • Cough (12%)
  • Dizziness (8%)
  • Back pain (6%)

Warnings for Aceon

  • Harm to unborn baby
  • Angioedema (swelling)
  • Low blood pressure
  • Worsening kidney problems
  • Low blood cell count
  • High levels of potassium
  • Dry cough
  • Liver problems

Prices with our coupons for Capoten vs. Aceon

Price Card Drug Icon
Captopril90 tablets / 25mg
$28.36$97.76
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Price Card Drug Icon
Perindopril90 tablets / 8mg
$53.69$200.43
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