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Biktarvy vs. Symtuza

Biktarvy is a combination antiretroviral medication. It contains bictegravir, emtricitabine, and tenofovir alafenamide (BIC/FTC/TAF). Biktarvy is a complete treatment for human immunodeficiency virus (HIV) infection. It's approved for adults and children who weigh at least 30 pounds with HIV. Biktarvy is a first-choice option for people starting HIV treatment. This medication comes as a single tablet and is taken by mouth once daily. It can cause side effects, such as nausea, diarrhea, and headache.

• Treatment of HIV in people weighing at least 30 lbs:
  • Who are starting treatment for the first time
  • Who've tried other HIV treatments that haven't worked well enough and who don't have resistance to certain HIV medications
  • Who want to switch HIV treatment and have a viral load of less than 50 copies/mL

• Higher creatine kinase levels (8%)
• Diarrhea (6%)
• Nausea (6%)
• Headache (5%)

• Worsening of hepatitis B infection in people with HIV and hepatitis B
• Overactive immune system
• Kidney problems
• Liver problems and lactic acidosis
• Interaction with other medications

Symtuza is a combination medication that treats human immunodeficiency virus (HIV). It's a tablet that contains three antiretroviral (ARV) medications — darunavir, emtricitabine, and tenofovir alafenamide — and a "booster" that helps the ARVs work better against the virus called cobicistat . Symtuza, also known as DRV/c/TAF/FTC, is a complete therapy for people with HIV weighing at least 88 pounds. It's taken once daily with food. Some common side effects of Symtuza include nausea and diarrhea.

• Treatment of HIV

• Diarrhea (9%)
• Rash (8%)
• Nausea (6%)
• Feeling tired (4%)
• Headache (3%)

• Worsening of hepatitis B infection in people with HIV and hepatitis B
• Liver problems and lactic acidosis
• Severe skin reactions and allergic reactions
• Overactive immune system
• Kidney problems
• Changes in body fat
• Bleeding in people with hemophilia
• Interactions with other medications