Key takeaways
Azelaic acid (Finacea) and tretinoin (Retin-A) are both prescription medications, but they treat different conditions. Azelaic acid (Finacea) is a dicarboxylic acid used topically to treat mild-to-moderate rosacea, while tretinoin (Retin-A) is an topical medication used to treat acne in adults and children 12 years and older. Azelaic acid is applied to the skin as a gel or foam twice daily, while tretinoin (Retin-A) is available as a cream or a gel applied to the skin once daily. Both medications are available as a lower-cost generic. Common side effects of azelaic acid include mild burning and itching, while tretinoin can cause skin irritation, redness, and peeling. Azelaic acid is generally considered safe during pregnancy, but tretinoin isn't typically recommended for use during pregnancy. Tretinoin may cause your acne to get worse at the beginning of treatment, but it should get better as you continue using the medication.
