Key takeaways
Aleve (naproxen sodium) and Tylenol (acetaminophen) are both over-the-counter medications used to relieve pain and reduce fever, but have a few differences between them. Unlike Tylenol, Aleve also works to treat inflammation and swelling, and is typically taken every 6 to 8 hours. Tylenol doesn't last as long, and is usually taken every 4 to 6 hours. Common side effects of Aleve include stomach upset, dizziness, and headache. On the other hand, Tylenol has fewer side effects, but can cause liver damage if taken in high doses or with alcohol. Both medications are available as a lower-cost generic. Tylenol is available in many forms, including tablets, liquids, and suppositories, Aleve is only available as a tablet.
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