Aptiom (eslicarbazepine) helps control seizures if you have partial-onset epilepsy. It can be used in people aged 4 years and older, but it interacts with some other medications and can be expensive if not covered by insurance.
Partial-onset seizures
Aptiom (eslicarbazepine) is an antiepileptic (anti-seizure) medication. It's not entirely clear how this medication works, but it's thought to target the activity of sodium channels in the brain. This might help calm down signaling from nerves and brain activity, which can help prevent seizures.
Source: DailyMed
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Can be used on its own, or with other seizure medications for better seizure control
Convenient, taken once daily
Tablets can be crushed (doesn't come in liquid form)
Causes dizziness, headache, and vision problems quite often
Can't take if you're allergic to oxcarbazepine (Trileptal)
Brand name only, so it can be more expensive than other alternatives
Take Aptiom (eslicarbazepine) with or without food.
You can crush the tablet if you're unable to swallow it whole.
Don't stop taking Aptiom (eslicarbazepine) without talking to your provider first. Stopping it too suddenly can cause seizures due to withdrawal effects.
If you notice a change in your mood, thoughts, or feelings, or if your child is behaving abnormally after taking Aptiom (eslicarbazepine), let your provider know. If you have thoughts of hurting yourself, call 911 or get medical help right away.
Aptiom (eslicarbazepine) can cause dizziness, drowsiness, tiredness, weakness, or difficulty with movement and coordination. Be careful driving or doing anything requiring concentration until you know how this medication affects you. Let your provider know if these side effects don't go away or are too bothersome.
Aptiom (eslicarbazepine) interacts with many medications, including other antiepileptics. This can affect the levels of Aptiom (eslicarbazepine) or other medications in your body, making them not work as well or lead to more side effects. Make sure to tell your provider and pharmacist about all the medications that you take, including over-the-counter medications and supplements.
Aptiom (eslicarbazepine) can make hormonal birth control not work as well. Make sure to use additional non-hormonal birth control (like condoms) while taking Aptiom (eslicarbazepine). This will help make sure your birth control works well and prevent unwanted pregnancies. Talk to your provider about what non-hormonal birth control options are best for you.
Aptiom (eslicarbazepine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Antiepileptic (anti-seizure) medications like Aptiom (eslicarbazepine) can raise your risk of suicide or thoughts of suicide. Watch for any new or worsening depression and any unusual changes in mood, especially during the first few months of taking this medication or if your dose changes. Report anything concerning to your provider. If you have thoughts of hurting yourself, call 911 or seek medical attention immediately.
Risk factors: Previous allergic reaction to oxcarbazepine (Trileptal) | Previous skin reaction to oxcarbazepine (Trileptal) or carbamazepine (Tegretol)
Aptiom (eslicarbazepine) can cause severe allergic reactions, including symptoms such as rash, hives, difficulty breathing, or swelling of the face or mouth. Severe skin reactions happen rarely but can be life-threatening. If not treated quickly, certain allergic reactions can lead to abnormal blood cell counts and damage to important organs, such as your liver, kidneys, or heart. Let your provider and pharmacist know if you've had an allergic reaction to oxcarbazepine (Trileptal) or carbamazepine (Tegretol), since their chemical structures are very similar to Aptiom (eslicarbazepine). Get medical help right away if you notice a rash, fever, swollen lymph nodes, flu-like symptoms, or swelling of the mouth, face, or throat.
Risk factors: Taking higher doses of Aptiom (eslicarbazepine) | Taking diuretics (water pills) or other medications that lower sodium levels in the blood
Aptiom (eslicarbazepine) can cause low sodium levels in the blood. This is more likely to happen if you take other medications that lower sodium levels, such as diuretics (water pills). If your sodium drops too low, it can be dangerous and lead to comas or even death. Your provider will monitor your blood sodium levels and other electrolyte levels on a regular basis while you're taking Aptiom (eslicarbazepine). Let your provider know if you experience severe headaches, trouble concentrating, forgetfulness, confusion, muscle weakness or spasms, or unsteadiness at any point while taking this medication. Get medical help right away if you experience more serious symptoms, such as hallucinations (seeing or hearing things that aren't real), more seizures than usual, or fainting.
Risk factors: When the dose of Aptiom (eslicarbazepine) is raised | Age 60 years or older | Also taking carbamazepine (Tegretol)
Aptiom (eslicarbazepine) can cause dizziness and problems with balance, movement, or coordination. It can also cause sleepiness, tiredness, or weakness, and can affect your memory or make it harder to think or act quickly. You can also have eyesight problems from taking Aptiom (eslicarbazepine), such as double or blurred vision. In general, these effects usually happen when you first start the medication, or when you switch to a higher dose. Avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how Aptiom (eslicarbazepine) affects you. Let your provider know if these side effects are too bothersome.
Risk factors: Stopping Aptiom (eslicarbazepine) suddenly
Don't stop taking Aptiom (eslicarbazepine) without talking to your provider first. Antiepileptic (anti-seizure) medications like Aptiom (eslicarbazepine) shouldn't be stopped too suddenly, since this can lead to seizures due to medication withdrawal. If it's necessary to stop taking it, your provider will instruct you on how to lower your dose slowly.
Aptiom (eslicarbazepine) can cause liver injury. This is usually mild, but can rarely lead to dangerous liver damage. Your provider will check your liver tests before you start this medication and regularly afterwards to make sure it doesn't become a serious problem. If you notice severe nausea, vomiting, right-sided stomach pain, fatigue, low or no appetite, or yellowing of the skin or eyes, seek medical help right away.
Adults: The typical starting dose is 400 mg or 800 mg by mouth once daily. The dose is raised weekly based on how well you respond to the medication. The typical long-term (maintenance) dose is 800 mg to 1,600 mg once daily.
Children 4 to 17 years of age: The dose is based on your child's weight and given by mouth once daily. The dose is raised weekly based on how well your child is responding to the medication. The starting dose ranges from 200 mg to 400 mg once daily, and the long-term (maintenance) dose ranges from 400 mg to 1,200 mg once daily.
Your dose might differ if you have kidney problems or if you take certain other antiepileptics (e.g., carbamazepine (Tegretol), phenytoin (Dilantin), primidone (Mysoline)).
Allergy to oxcarbazepine (Trileptal)
Treatment for partial-onset seizures - for people at least 1 month of age (Vimpat brand) or at least 4 years old (generic)
Add-on treatment for primary generalized tonic-clonic (PGTC) seizures - for people at least 4 years old (Vimpat brand only)
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