Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Vimpat (lacosamide) and Aptiom (eslicarbazepine) are both oral prescription antiepileptic medications used to treat seizures, but they have some key differences. Vimpat can be taken twice daily for partial-onset seizures and as add-on treatment for primary generalized tonic-clonic (PGTC) seizures, whereas Aptiom is taken once a day and is only approved for partial-onset seizures. Both medications are available as low-cost generics which can be used in children as young as 4 years old. However, brand-name Vimpat can be used in children as young as 1 month for the treatment of partial-onset seizures. Vimpat is available as a tablet and oral solution, whereas Aptiom is only available in tablet form, but can be crushed if you have difficulty swallowing. Both medications can cause dizziness and other side effects, but Aptiom has a higher risk of causing low sodium levels in your blood. Unlike Aptiom, Vimpat is a Schedule V controlled substance, meaning it has a potential for misuse and dependence.
Vimpat (lacosamide)
Aptiom (eslicarbazepine)
Vimpat (lacosamide)
Aptiom (eslicarbazepine)
Summary of Vimpat vs. Aptiom
Summary for Antiepileptic
Prescription only
Vimpat (lacosamide) is an antiepileptic (anti-seizure) medication. It can be taken on its own or with other antiepileptics to treat partial-onset seizures (also known as focal seizures). It's also an add-on therapy to treat primary generalized tonic-clonic (PGTC) seizures (also known as grand mal seizures). The dosage is adjusted based on how well it works and whether you're having any side effects. Vimpat (lacosamide) is available in both brand-name and generic versions. It's classified as a schedule V controlled substance.
Summary for Antiepileptic
Prescription only
Aptiom (eslicarbazepine) helps control seizures if you have partial-onset epilepsy. It can be used in people aged 4 years and older, but it interacts with some other medications and can be expensive if not covered by insurance.
Indications of Vimpat vs. Aptiom
Indications for
•Treatment for partial-onset seizures - for people at least 1 month of age (Vimpat brand) or at least 4 years old (generic)
•Add-on treatment for primary generalized tonic-clonic (PGTC) seizures - for people at least 4 years old (Vimpat brand only)
Indications for
•Partial-onset seizures
Pros and Cons of Vimpat vs. Aptiom
Pros and Const for Antiepileptic
Pros
•Can take the medication on its own for partial-onset seizures (also called focal seizures)