Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Vimpat (lacosamide) and Aptiom (eslicarbazepine) are both oral prescription antiepileptic medications used to treat seizures, but they have some key differences. Vimpat can be taken twice daily for partial-onset seizures and as add-on treatment for primary generalized tonic-clonic (PGTC) seizures, whereas Aptiom is taken once a day and is only approved for partial-onset seizures. Both medications are available as low-cost generics which can be used in children as young as 4 years old. However, brand-name Vimpat can be used in children as young as 1 month for the treatment of partial-onset seizures. Vimpat is available as a tablet and oral solution, whereas Aptiom is only available in tablet form, but can be crushed if you have difficulty swallowing. Both medications can cause dizziness and other side effects, but Aptiom has a higher risk of causing low sodium levels in your blood. Unlike Aptiom, Vimpat is a Schedule V controlled substance, meaning it has a potential for misuse and dependence.
Lacosamide (Vimpat)
Aptiom (eslicarbazepine)
Lacosamide (Vimpat)
Aptiom (eslicarbazepine)
Summary of Vimpat vs. Aptiom
Summary for Antiepileptic
Prescription only
Lacosamide (Vimpat) is an antiepileptic. People 1 month and older can take it on its own or with other antiepileptics for partial-onset seizures (also called focal aware seizures). It's also an add-on medication for people 4 years and older who have primary generalized tonic-clonic (PGTC) seizures (or grand mal seizures). Lacosamide (Vimpat) comes as tablets and an oral solution that's taken by mouth twice a day. It's also available as an injection that's used in the hospital. Side effects include dizziness, headache, and nausea. Lacosamide (Vimpat) comes as both brand-name and generic versions, but it's a controlled substance.
Summary for Antiepileptic
Prescription only
Aptiom (eslicarbazepine) helps control seizures if you have partial-onset epilepsy. It can be used in people aged 4 years and older, but it interacts with some other medications and can be expensive if not covered by insurance.
Indications of Vimpat vs. Aptiom
Indications for
•Partial-onset seizures (or focal aware seizures) - for people at least 1 month of age