Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Trileptal (oxcarbazepine) and rufinamide (Banzel) are both antiepileptic medications, but they are used for different types of seizures. Trileptal is used to treat partial-onset seizures and can be taken alone or with other seizure medications. It’s available in both immediate-release and extended-release forms (Oxtellar XR). The immediate-release form can be used in children as young as 2 years old. On the other hand, rufinamide is specifically used for seizures linked to Lennox-Gastaut syndrome (LGS) and can be given to adults and children as young as 1 year old. Unlike Trileptal, rufinamide must be taken with other seizure medications and with food for full absorption. Both medications can cause dizziness and drowsiness, but rufinamide also has a risk of heart rhythm problems and requires careful monitoring for severe allergic reactions, especially in children under 12. Both medications are available as a low-cost generic.
Oxcarbazepine (Trileptal)
Rufinamide (Banzel)
Oxcarbazepine (Trileptal)
Rufinamide (Banzel)
Summary of Trileptal vs. Banzel
Summary for Antiepileptic
Prescription only
Oxcarbazepine (Trileptal) is used to treat partial-onset seizures (also called focal aware seizures). This antiepileptic is for people 2 years of age and older. It helps calm the brain to keep seizures from happening. Oxcarbazepine (Trileptal) comes as immediate-release tablets and an oral suspension. You take it by mouth twice a day. Some common side effects include dizziness, nausea, and headaches. Immediate-release oxcarbazepine comes in both brand-name and generic versions. You can take it by itself or with other anti-seizure medications.
Summary for Antiepileptic
Prescription only
Rufinamide (Banzel) is an antiepileptic medication that helps control seizures due to a type of epilepsy called Lennox-Gastaut syndrome (LGS). It's approved as add-on treatment to other anti-seizure medications for adults and children 1 year of age and older. Rufinamide (Banzel) is typically taken by mouth twice a day. It comes in tablet and oral suspension form. Rufinamide (Banzel) isn't a controlled substance, but it commonly causes drowsiness and vomiting as side effects.