How Much Is Xiidra Without Insurance?
Without coverage, the cost of 1 carton of Xiidra (60 ampules) can exceed $700. Learn more about how much Xiidra costs without insurance and savings with GoodRx.
Xiidra
Used for Dry Eye
Used for Dry Eye
Xiidra (lifitegrast) is an eye drop medication that treats dry eye in adults. It belongs to a drug class called LFA-1 antagonists. It's thought to help lower inflammation and other symptoms of dry eye. Usually, you need to use Xiidra (lifitegrast) every day. You put 1 drop into each eye twice a day. Side effects include temporary eye irritation and unclear vision. At this time, Xiidra (lifitegrast) is available only as a brand medication. There's no generic version yet.
What is Xiidra (lifitegrast)?
What is Xiidra (lifitegrast) used for?
How Xiidra (lifitegrast) works
Xiidra (lifitegrast) is a lymphocyte function-associated antigen-1 (LFA-1) antagonist. It blocks a protein called LFA-1.
LFA-1 normally causes an immune response in the eye. This can lead to inflammation (e.g., redness, swelling) and dry eye.
It's not exactly clear how Xiidra (lifitegrast) works to help with dry eye. But it's thought that by blocking LFA-1, it helps lower inflammation and ease dry eye symptoms.
When does Xiidra (lifitegrast) start working?Time passed since treatment started:
Drug facts
| Common Brands | Xiidra |
|---|---|
| Drug Class | LFA-1 antagonist |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Prescription only |
More on Xiidra (lifitegrast) essentials
Side effects of Xiidra (lifitegrast)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Eye irritation (5-25%)
- Strange taste in the mouth (5-25%)
- Unclear vision (5-25%)
Less Common Side Effects
- Blurred vision
- Eye redness
- Watery eye
- Eye discharge
- Eye discomfort
- Itchy eye
- Headache
- Sinus infection
When do Xiidra (lifitegrast) possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Eye irritation
Strange taste in the mouth
Unclear vision
More on Xiidra (lifitegrast) side effects
The following Xiidra (lifitegrast) side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- New or worsening eye pain, redness, irritation, or discharge
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Blurry vision
- Change in taste
- Eye irritation or itching
- Headache
- Increased tears after use
Get your GoodRx coupon
$914.97
GoodRx discount
$717.29
Pros and cons of Xiidra (lifitegrast)
Pros
- Works to help treat dry eye in the long run
- Might be less likely to cause burning in the eyes than Restasis (cyclosporine)
Cons
- Won't give you instant relief and have to take for a couple weeks before it starts working
- Not approved for people younger than 17 years old
Pharmacist tips for Xiidra (lifitegrast)
- Keep the single-use containers of Xiidra (lifitegrast) at room temperature. Don't take them out of the foil pouch until you're ready to use the medication. These pouches help protect the medication from light.
- Wash your hands before each time you use Xiidra (lifitegrast). Also don't let the tip of the container touch your eye or any other surface. This helps you avoid getting germs in your eyes, which can prevent eye infections.
- If you wear contact lenses, take them out before using Xiidra (lifitegrast). Then, wait at least 15 minutes afterwards to put them back in.
- Use the eye drops right after you open the Xiidra (lifitegrast) container. Each container has enough medication for 1 drop in both eyes.
- How to use Xiidra (lifitegrast) eye drops: Hold the container upright, and tap the top to move all the medication to the bottom. Twist off the tab to open it. Tilt your head backwards or lie down with your face up. Then, gently pull down your lower eyelid. While looking up, squeeze out 1 drop into the space between your lower eyelid and your eye. If you miss, you can try again. Do the same thing for the other eye.
- After placing Xiidra (lifitegrast) in your eye, close your eye and press one finger to the inner corner of your eye by the nose for a couple minutes. This helps your eye absorb the drop and that not too much medication drains into your tear duct.
- Throw away the Xiidra (lifitegrast) container after using it, even if there's some medication left. It doesn't have any preservatives in it. This can make it easier for germs to grow in any leftover medication. Using it again could lead to eye infections.
- If you need to use another eye medication with Xiidra (lifitegrast), wait at least 5 minutes between them. This gives your eye time to absorb each medication.
Risks and warnings for Xiidra (lifitegrast)
Xiidra (lifitegrast) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk of contamination
Remember to wash your hands before using Xiidra (lifitegrast). Don't touch the tip of the Xiidra (lifitegrast) container with your fingers. And don't let the tip touch your eye or any surface. These steps help prevent the medication from getting contaminated with germs. This lowers your chance of eye infection and injury to the eye.
Xiidra (lifitegrast) dosage
The average cost for 1 carton of 60 ampules of 5% of Xiidra (lifitegrast) is $0.00 with a free GoodRx coupon. This is 100.00% off the average retail price of $914.97. 
Carton
Carton| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 60 ampules of 5% | 1 carton | $0.00 | $0.00 |
Typical dosage for Xiidra (lifitegrast)
The typical dose is 1 drop into each eye twice daily (about 12 hours apart).
How much does Xiidra (lifitegrast) cost?
To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
Xiidra (brand)
$0.00
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What are alternatives to Xiidra (lifitegrast)?
There are a number of medications that your doctor can prescribe in place of Xiidra (lifitegrast). Compare a few possible alternatives below.
News about Xiidra (lifitegrast)
Bad Taste, Blurry Vision, and More: 7 Xiidra Side Effects You Should Know About
Xiidra may cause mild eye irritation and blurry vision. Read on to learn more side effects of Xiidra, including serious risks and how to manage them.
Xiidra vs. Restasis: 6 Ways These Dry Eye Treatments Compare
When your eyes feel tight and dry, sometimes only prescription eye drops will help. Compare the effects of Xiidra versus Restasis to help decide which one is right for you.
What Works to Treat Dry Eye? The Best Eye Drops and Home Remedies
You can treat chronic dry eyes with prescription medication, OTC eye drops, and even home remedies like omega-3. Explore the best eye drops for dry eye relief here.
Dry Eyes, Blurred Vision, Light Sensitivity: How Autoimmune Diseases Affect Your Eyes
Autoimmune diseases are a collection of diseases that cause the immune system to attack different parts of the body, including the eyes. Find out more at GoodRx.
Xiidra (lifitegrast) images
