Key takeaways
Miebo (perfluorohexyloctane) and Cequa (cyclosporine) are both prescription eye drops used to treat dry eyes in adults. However, they belong to different medication classes and work in distinct ways. Miebo is a semifluorinated alkane that forms a protective layer on the eye to prevent tears from evaporating, while Cequa is an immunosuppressant that lowers inflammation and helps your eyes produce more tears. Miebo is applied four times a day, whereas Cequa is used twice a day. Miebo is only available as a brand name medication, while Cequa also lacks a generic version. Common side effects of Miebo include blurry vision and eye redness, while Cequa may cause eye pain and redness. Both medications should not be used with contact lenses, but the waiting period before reinserting lenses is 30 minutes for Miebo and 15 minutes for Cequa.
