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Paroxetine Coupon - Paroxetine 20mg tablet

paroxetine

Generic Paxil
Used for Anxiety, Depression, Menopause, Obsessive-Compulsive Disorder, Panic Disorder, PTSD

Paroxetine (also known by it's brand name Paxil) is a selective serotonin reuptake inhibitor (SSRI), used for different types of anxiety problems and depression. It's available as a brand name and generic version, and it comes as an immediate-release tablet, an oral suspension, and an extended-release tablet. Possible side effects include nausea, sexual side effects, and weight gain. It can also cause withdrawal symptoms (e.g., headache, trouble sleeping, anxiety) if you suddenly stop taking it.

Reviewed by:Last reviewed on July 13, 2023
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What is Paroxetine (Paxil)?

How Paroxetine (Paxil) works

Paroxetine (Paxil) is a selective serotonin reuptake inhibitor (SSRI). It works by raising the levels of serotonin, an important chemical in your brain that's involved with regulating your mood.

When does Paroxetine (Paxil) start working?Time passed since treatment started:
HOURS
DAYS
WEEKS
Initial effect
MONTHS
Full effect

Drug facts

Common BrandsPaxil, Paxil CR
Drug ClassSSRI
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Side effects of Paroxetine (Paxil)

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Abnormal ejaculation (up to 28%)
  • Nausea (up to 25%)
  • Weakness (up to 22%)
  • Sleepiness or trouble sleeping (up to 24%)
  • Dry mouth (up to 18%)
  • Constipation (up to 16%)
  • Sweating (up to 14%)
  • Dizziness (up to 14%)
  • Diarrhea (up to 12%)
  • Low libido (up to 12%)
  • Shakiness (up to 11%)

Less Common Side Effects

  • Blurry vision
  • Nervousness
  • Low appetite
  • Anxiety
  • Numbness or tingling

Please note: Side effects listed here were reported by people taking paroxetine (Paxil) for OCD, SAD, and panic disorder in clinical studies. The side effects you experience from paroxetine (Paxil) might differ.

Paroxetine (Paxil) serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Suicidal thoughts or behaviors
  • Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, distress, seizures, distress, hallucinations, coma
  • Seizures
  • Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
  • Severe bleeding: bruising that doesn't improve, black-colored stools, pink or red-colored urine, coughing up or vomiting blood, or unusual bleeding from the nose or gums
  • Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren't real), seizures, unconsciousness
When do Paroxetine (Paxil) possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Sexual problems
Nausea
Sleepiness
Dizziness
Diarrhea
Thoughts of self-harm
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Paroxetine (Paxil) side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Agitation

chest pain or tightness

chills

cold sweats

confusion

difficulty with breathing

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position

fast, pounding, or irregular heartbeat or pulse

muscle pain or weakness

skin rash

Rare

Absence of or decrease in body movements

bigger, dilated, or enlarged pupils (black part of the eye)

difficulty with speaking

dry mouth

fever

inability to move the eyes

incomplete, sudden, or unusual body or facial movements

increased sensitivity of the eyes to light

poor coordination

red or purple patches on the skin

restlessness

seizures

shivering

sweating

talking, feeling, and acting with excitement and activity you cannot control

trembling or shaking, or twitching

Incidence not known

Back, leg, or stomach pains

blindness

blistering, peeling, or loosening of the skin

blue-yellow color blindness

blurred vision

constipation

cough or hoarseness

dark urine

decreased frequency or amount of urine

decreased vision

difficulty with swallowing

electric shock sensations

eye pain

fainting

general body swelling

headache

high fever

hives or itching skin

inability to move the arms and legs

inability to sit still

increased thirst

incremental or ratchet-like movement of the muscle

joint pain

light-colored stools

lockjaw

loss of appetite

loss of bladder control

lower back or side pain

muscle spasm, especially of the neck and back

muscle tension or tightness

need to keep moving

painful or difficult urination

painful or prolonged erection of the penis

pale skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

raised red swellings on the skin, the buttocks, legs, or ankles

red, irritated eyes

sensitivity to the sun

skin redness or soreness

slow heart rate

sores, ulcers, or white spots on the lips or in the mouth

spasms of the throat

stiff muscles

stomach pain

sudden numbness and weakness in the arms and legs

swelling of the breasts

swelling of the face, fingers, or lower legs

swollen or painful glands

tightness in the chest

unexpected or excess milk flow from the breasts

unusual bleeding or bruising

unusual tiredness or weakness

vomiting

weight gain

yellowing of the eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

belching

decreased appetite

decreased sexual ability or desire

heartburn

pain or tenderness around the eyes and cheekbones

passing gas

problems with urinating

runny or stuffy nose

sexual problems, especially ejaculatory disturbances

sleepiness or unusual drowsiness

stomach discomfort or upset

trouble sleeping

Less common

Abnormal dreams

change in sense of taste

congestion

discouragement, feeling sad, or empty

drugged feeling

fast or irregular breathing

feeling of unreality

headache, severe and throbbing

increased appetite

itching of the vagina or genital area

itching, pain, redness, or swelling of the eye or eyelid

lack of emotion

loss of interest or pleasure

lump in the throat

menstrual changes

pain during sexual intercourse

problems with memory

sense of detachment from self or body

sneezing

thick, white vaginal discharge with no odor or with a mild odor

tightness in the throat

tingling, burning, or prickling sensations

trouble concentrating

voice changes

watering of the eyes

weight loss

yawn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Pros and cons of Paroxetine (Paxil)

Pros

  • Only needs to be taken once daily
  • Available as a tablet and oral liquid
  • Can be taken with or without food
  • Can be used for many different mental health conditions
  • Can be helpful for people who have both anxiety and depression

Cons

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Pharmacist tips for Paroxetine (Paxil)

pharmacist
  • You can take paroxetine (Paxil) with or without food, but paroxetine (Paxil) also commonly causes nausea, so taking it with food might help.
  • Don't change your dose or suddenly stop taking paroxetine (Paxil) without talking to your provider first. Doing so can cause withdrawal symptoms like nausea, headache, and sleeping problems. Follow your provider's instructions to lower your dose slowly over a period of time to stop the medication completely.
  • Paroxetine (Paxil) can cause sexual side effects, such as ejaculation problems in males, low sex drive, and erectile dysfunction. These side effects are likely to go away after you stop taking paroxetine (Paxil).
  • Paroxetine (Paxil) can make you sleepy and dizzy. Don't drive or do anything requiring concentration until you know how this medication affects you.
  • Don't drink alcohol while taking paroxetine (Paxil) because it can worsen side effects (e.g., drowsiness, dizziness) as well as worsen your depression symptoms. Also, don't drive or do anything requiring concentration until you know how this medication affects you.
  • Antidepressant medications like paroxetine (Paxil) can raise the risk of suicidal thoughts. Contact your provider right away if you or your loved ones notice any new or worsening changes in your behavior or mood while taking the medication.
  • Paroxetine (Paxil) can interact with a lot of commonly used medications. For example, it can raise your risk for serious bleeds, especially if you're also taking other blood thinners. Paroxetine (Paxil) can also lower how well tamoxifen (Nolvadex, Soltamox) works. Make sure to tell your provider and pharmacist about all of the medications you're taking before starting paroxetine (Paxil). Also, don't start any new medications while taking paroxetine (Paxil) without talking to your provider first.
  • If you're taking the extended-release (Paxil CR) tablets, make sure to swallow the tablet whole. Don't chew or crush the ER tablets because it's specially created to be released at a specific rate in your body. If you break or crush the tablets, it can change how your body absorbs the medication and cause serious side effects.

More tips for paroxetine (Paxil) suspension:

  • Shake the suspension well before drawing up your dose. Make sure to use an oral syringe or medication dosing cup to measure out your paroxetine (Paxil) liquid dose. Don't use household spoons because they aren't accurate and might cause you to take the wrong dose.
  • Store the paroxetine (Paxil) liquid at room temperature in the original bottle it came in from the pharmacy.
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Common questions about Paroxetine (Paxil)

Yes, some people do experience weight gain from taking paroxetine (Paxil). But the amount of weight gained differs from one person to another. To lower your risk for weight gain while taking paroxetine (Paxil), make sure to have a healthy diet and regular exercise routine. Contact your provider if you're uncomfortable with how much weight you've gained while on paroxetine (Paxil). They might give you medications to treat the weight gain or switch you to a different medication.

Yes, sleepiness is a possible side effect of paroxetine (Paxil) that usually goes away after a few weeks of taking it. On the other hand, some people can also have difficulty sleeping from paroxetine (Paxil). When you first start paroxetine (Paxil), see how you respond to the medication and adjust the timing of your dose accordingly. If you notice you feel sleepy after taking your dose, take it at bedtime. If you notice paroxetine (Paxil) makes it difficult to fall asleep, take it in the morning.

No, paroxetine (Paxil) isn't a controlled substance because it doesn't have a risk of addiction, misuse, or dependence.

It'll depend on why you're taking paroxetine (Paxil). For example, if you're taking this medication for depression, you might notice improvements in your mood 2 weeks after starting paroxetine (Paxil). But, it can take about 1 to 2 months before you feel its full effects. You might feel side effects (e.g., nausea, sleepiness, weight gain) before feeling any improvement in your symptoms. Contact your provider if you're not sure if paroxetine (Paxil) is working, but don't stop taking the medication until you've talked to them because you might get withdrawal symptoms like headache, trouble sleeping, and anxiety.

It takes about 5 days for most of paroxetine (Paxil) to leave your body after your last dose. This time frame is estimated based on the half-life of paroxetine (Paxil). It can differ from person to person depending on other factors, such as your age and whether if you have kidney or liver problems.

No. While both paroxetine (Paxil) and alprazolam (Xanax) can be used to treat anxiety problems, they are two completely different medications that work in different parts of the brain. Paroxetine (Paxil) is a selective serotonin reuptake inhibitor (SSRI), whereas alprazolam (Xanax) is a benzodiazepine.

While paroxetine (Paxil) isn't FDA-approved for premature ejaculation, studies from the American Urological Association show it works well for condition. Additionally, a review of multiple studies, which is the strongest type found paroxetine (Paxil) worked well for premature ejaculation, even compared to some other SSRIs. If you want to know more about options for treating premature ejaculation, talk with your provider.

Research shows that paroxetine (Paxil) can get into breastmilk in low amounts. It's possible that it can cause mild side effects in breastfed babies, such as restlessness and more crying. But, paroxetine (Paxil) is considered to be one of the safer options to use while breastfeeding. If you've any questions, talk with your provider about the benefits and risks of taking paroxetine (Paxil) while breastfeeding.

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Risks and warnings for Paroxetine (Paxil)

Paroxetine (Paxil) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Worsening depression, suicidal thoughts, and unusual behavior

  • Risk factors: Age under 24 years old | History of other mental health conditions

Black Box Warning Taking paroxetine (Paxil) can make your depression worse and cause you to have thoughts of suicide or harming yourself. The risk is highest if you're 24 years of age or younger, during the first few weeks of taking the medication, and when your dose changes. If you or anyone around you notice that you have suicidal thoughts or unusual behavior (e.g., anxiety, panic attacks, difficulty sleeping, feeling angry or irritated, restlessness) while taking paroxetine (Paxil), get medical help right away.

Serotonin syndrome

  • Risk factors: Taking other medications that raise serotonin levels in your brain

Some people taking paroxetine (Paxil) have developed a rare, but potentially life-threatening condition called serotonin syndrome. This condition happens where there's too much serotonin in the brain. Your risk for serotonin syndrome is higher if you use paroxetine (Paxil) with other medications that can raise your serotonin levels, such as certain antidepressants, mental health medications, pain medications, and migraine medications. Let your provider know about all the medications you take before starting paroxetine (Paxil). Also, don't start any new medications without talking to your provider first. Symptoms of serotonin syndrome include fast heart rate, sweating, muscle stiffness or spasms, fever, and confusion. Get medical help right away if you have any of these symptoms.

Risk of harm to unborn babies

  • Risk factors: Currently pregnant

Paroxetine (Paxil) isn't recommended for pregnant females because there's a risk it can cause severe harm (e.g., heart problems, body deformities) to unborn babies. Make sure to tell your provider if you're pregnant or thinking of becoming pregnant soon before starting paroxetine (Paxil). They can talk with you about safer options.

Sexual problems

Paroxetine (Paxil) can cause sexual problems, include low libido and problems with ejaculation. If you're experiencing these side effects, talk with your provider. They can talk with you about possible options, such as lowering your dose of paroxetine (Paxil) or switching to a different medication.

Withdrawal

  • Risk factors: Stopping paroxetine (Paxil) suddenly

Stopping paroxetine (Paxil) suddenly can cause withdrawal symptoms such as nausea, anxiety, agitation, flu-like symptoms, trouble sleeping, and dizziness. If you want to or need to stop taking paroxetine (Paxil), ask your healthcare provider how to do so safely over time. Never try to stop paroxetine (Paxil) on your own and without the supervision of your healthcare provider.

Risk of bleeding

  • Risk factors: Taking blood-thinners or other medications that raise your risk of bleeding

Paroxetine (Paxil) can raise your risk of bleeding or bruising, especially if you're also taking antiplatelets (e.g., aspirin, clopidogrel (Plavix)) or anticoagulants (e.g., warfarin (Coumadin), apixaban (Eliquis), rivaroxaban (Xarelto)). Get medical help if you get bruising that doesn't improve, black-colored stools, pink or red-colored urine, coughing up or vomiting blood, or unusual bleeding from the nose or gums.

Not for use alone in bipolar disorder

Depression can be the first sign of bipolar disorder. If you're at risk for bipolar disorder, taking antidepressants, like paroxetine (Paxil), by themselves can trigger a bipolar manic episode. Before starting paroxetine (Paxil), your provider will check to see if you have or are at risk for bipolar disorder. Paroxetine (Paxil) isn't used to treat bipolar depression. Talk to your provider right away if you or your loved ones notice unusual changes in your behavior, such as racing thoughts, restlessness, getting easily distracted, or unusual talkativeness.

Glaucoma

  • Risk factors: History of angle-closure glaucoma

Paroxetine (Paxil) can lead to or worsen angle-closure glaucoma. You might need to see your optometrist regularly and get eye exams to check your eyes and make sure your vision isn't worsening. Contact your provider if you notice changes in your vision after starting paroxetine (Paxil).

Low blood sodium levels

  • Risk factors: Older people | Taking diuretic medications

Paroxetine (Paxil) can cause low blood sodium levels. Your provider might closely monitor your blood sodium levels before and during treatment with paroxetine (Paxil). Get medical help right away if you experience weakness, confusion, difficulty concentrating, headache, or memory problems because these could be signs of low blood sodium levels, which is a medical emergency.

Seizures

  • Risk factors: History of seizures | Health conditions that make it easier to get seizures

Paroxetine (Paxil) hasn't been well-studied in people who have seizures. Before starting this medication, let your provider know if you have a history of seizures or have a medical condition that puts you at risk for getting seizures. They can discuss with you whether paroxetine (Paxil) is a good option.

Risk of abnormal heart rhythm from interactions

  • Risk factors: Personal or family history of long QT syndrome | Taking other medications that cause QT prolongation

Don't take paroxetine (Paxil) with thioridazine (Mellaril) or pimozide (Orap). Paroxetine (Paxil) can interact with these medications and raise their levels in your body. This puts you at risk for side effects like QT prolongation, which affects your heart rhythm.

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Paroxetine (Paxil) dosage

The average cost for 90 tablets of 20mg of Paroxetine (Paxil) is $10.00 with a free GoodRx coupon. This is 0.00% off the average retail price of $10.00.
bottle of oral suspensionBottle of oral suspension
DosageQuantityPrice as low asPrice per unit
250ml of 10mg/5ml1 bottle$97.27$97.27
packagePackage
DosageQuantityPrice as low asPrice per unit
30 capsules of 7.5mg1 package$52.12$52.12
tabletTablet
DosageQuantityPrice as low asPrice per unit
10mg30 tablets$10.01$0.33
20mg90 tablets$10.00$0.11
30mg30 tablets$4.00$0.13
40mg30 tablets$9.00$0.30

Typical dosage for Paroxetine (Paxil)

Your provider will adjust your dose based on how well it's helping your symptoms, if your 65 years of age or older, have kidney or liver problems, or if you're having side effects.

  • Paroxetine (Paxil CR) extended-release tablet

    • Depression: The typical dose ranges from 25 mg to 62.5 mg by mouth once per day.
    • Panic disorder (PD): The typical dose ranges from 12.5 mg to 75 mg by mouth once per day.
    • Social anxiety disorder (SAD): The typical dose ranges from 12.5 mg to 37.5 mg by mouth once per day.
    • Premenstrual dysphoric disorder (PMDD): The typical dose ranges from 12.5 mg to 25 mg by mouth once per day. It can be taken every day throughout your menstrual cycle or daily starting 2 weeks before your period and through the first full day of your period.
  • Paroxetine (Paxil) immediate-release (IR) tablet and suspension

    • Depression, GAD, and PTSD: The typical dose ranges from 20 mg to 50 mg by mouth once per day.
    • Social anxiety disorder and OCD: The typical dose ranges from 20 mg to 60 mg by mouth once per day.
    • Panic disorder (PD): The typical dose ranges from 10 mg to 60 mg by mouth once per day.
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Interactions between Paroxetine (Paxil) and other drugs

Paroxetine (Paxil) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Paroxetine (Paxil). Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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Paroxetine (Paxil) contraindications

Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Paroxetine (Paxil) will not be safe for you to take.

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Paroxetine (Paxil) images

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