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Dexlansoprazole Coupon - Dexlansoprazole 60mg capsule

dexlansoprazole

Generic Dexilant
Used for Heartburn, GERD
Used for Heartburn, GERD

Dexlansoprazole (Dexilant) is a prescription medication used to treat conditions caused by too much stomach acid, such as heartburn or gastroesophageal reflux disease (GERD). It's a proton pump inhibitor (PPI), which means it blocks acid from "getting pumped" into the stomach. Dexlansoprazole (Dexilant) can be taken by adults and children ages 12 years and older. It's typically taken once daily, with or without food. Dexlansoprazole (Dexilant) doesn't cause many side effects, but some of the more common ones include diarrhea, nausea, and stomach pain.

Reviewed by:
reviewer
Ally Tsai, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on May 14, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Dexlansoprazole (Dexilant)?

What is Dexlansoprazole (Dexilant) used for?

How Dexlansoprazole (Dexilant) works

Dexlansoprazole (Dexilant) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach by blocking the final step of stomach acid production. This helps relieve heartburn and other stomach problems.

Are you looking for information on lansoprazole (Prevacid) instead?
When does Dexlansoprazole (Dexilant) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsDexilant
Drug ClassPPI
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Dexlansoprazole (Dexilant) essentials

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What are the side effects of Dexlansoprazole (Dexilant)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Adults
  • Diarrhea (5%)
  • Belly pain (4%)
  • Nausea (3%)
Children
  • Headache (more than 5%)
  • Belly pain (more than 5%)
  • Diarrhea (more than 5%)
  • Common cold (more than 5%)
  • Mouth and throat pain (more than 5%)

Other Side Effects

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Severe diarrhea
  • Kidney problems: urinating more or less than usual, fever, poor appetite
  • Lupus symptoms: joint pain, skin rash on arms or cheeks that gets worse in the sunlight
  • Serious allergic reaction: blistering, peeling, or bleeding skin; fever; chills

Source: DailyMed

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The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain, discomfort, tightness, or heaviness

confusion

continuing stomach pain

diarrhea

difficult or labored breathing

fast, irregular, pounding, or racing heartbeat or pulse

fever

headache

incoherent speech

joint pain, stiffness, or swelling

lightheadedness, dizziness, or fainting

muscle pain, cramps, or weakness

nausea

numbness or tingling in the hands, feet, or lips

pain or discomfort in the arms, jaw, leg, back, or neck

pounding in the ears

rash, hives

shakiness in the legs, arms, hands, or feet

sweating

swelling of the eyelids, face, lips, hands, or feet

swollen, painful, or tender lymph glands in the neck, armpit, or groin

unusual bleeding or bruising

vomiting

vomiting of blood or material that looks like coffee grounds

watery or bloody diarrhea

Incidence not known

Blistering, peeling, or loosening of the skin

chills

cough

drowsiness

muscle spasms (tetany) or twitching

red skin lesions, often with a purple center

red, irritated eyes

seizures

sores, ulcers, or white spots in the mouth or on the lips

swelling of the body, feet, or ankles

trembling

unusual weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Abnormal dreams

body aches or pain

bloated or full feeling

burning or itching around the anus

change in taste or bad, unusual, or unpleasant (after) taste

continuing ringing or buzzing or other unexplained noise in the ears

difficult or painful urination

difficulty with moving

ear congestion

ear pain

excess air or gas in the stomach or bowels

falls

feeling of constant movement of self or surroundings

loss in sexual ability, desire, drive, or performance

loss of voice

metallic taste

muscle or bone pain

passing gas

redness of the face, neck, arms, and occasionally, upper chest

runny or stuffy nose

sensation of spinning

sneezing

sore throat

sunburn

trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Dexlansoprazole (Dexilant)

thumbs-up

Pros

Can take with or without food

Only taken once a day

Granules inside the capsules can be mixed with water or applesauce, so convenient for people with difficulty swallowing pills

FDA-approved for children age 12 and older

thumbs-down

Cons

Long-term use might weaken bones and raise the risk of bone fracture(s)

Might cause a false-positive urine drug test

Not safe for people with severe liver problems

Can lower magnesium and vitamin B12 levels

pharmacist-tips

Pharmacist tips for Dexlansoprazole (Dexilant)

pharmacist

  • Typically, dexlansoprazole (Dexilant) can be taken with or without food.

    • Swallow dexlansoprazole (Dexilant) capsules whole. Don't chew or crush the capsules or the granules inside. Doing so can change how the medication gets absorbed into your body.

      • If you can't swallow dexlansoprazole (Dexilant) capsules, you can open the capsule and sprinkle the granules onto one tablespoon of applesauce. Once mixed, swallow the applesauce right away without chewing or crushing the granules. You can drink some cool water afterwards to make sure you've swallowed all the medication.

        • Dexlansoprazole (Dexilant) can be opened and the granules can be mixed with 20 mL of water. Take the mixture by mouth with an oral syringe. Refill the syringe with 10 mL of water and drink this to make sure you got all of the medication. Don't save any of the mixture for later, since the medication might not work as well anymore.

          • Dexlansoprazole (Dexilant) can interact with many medications. For example, taking dexlansoprazole (Dexilant) with warfarin (Coumadin) can raise the level of warfarin (Coumadin) in your body and put you at higher risk for bleeding. Let your care team know what medications you take or plan to take before you start dexlansoprazole (Dexilant), so they can help you check for interactions.

            • Don't take dexlansoprazole (Dexilant) for longer than prescribed by your primary care provider (PCP) to control your symptoms. Taking this medication long-term can raise your risk for certain side effects, such as bone fractures or diarrhea.

              • Dexlansoprazole (Dexilant) might not be a good option for you if you're looking for immediate relief from heartburn. But you can take other quick-acting antacids, such as calcium carbonate (Tums), along with dexlansoprazole (Dexilant) until the medication effect kicks in. Ask your care team about other medications you can take to relieve your heartburn.

                More on Dexlansoprazole (Dexilant) tips

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                faqs

                Frequently asked questions about Dexlansoprazole (Dexilant)

                When to take dexlansoprazole (Dexilant) morning or night?
                Dexlansoprazole (Dexilant) can be taken at any time of the day, with or without food. Follow your primary care provider's instructions on when to take this medication.
                How long does it take dexlansoprazole (Dexilant) to work?
                You might need to take dexlansoprazole (Dexilant) for 3 days to experience the maximum benefit of this medication. If you need immediate relief, consider taking an antacid, such as Tums (calcium carbonate), along with dexlansoprazole (Dexilant) until the medication effect kicks in.
                How to stop taking dexlansoprazole (Dexilant)?
                Talk with your healthcare team if you want to stop taking dexlansoprazole (Dexilant). If you've been taking dexlansoprazole (Dexilant) for more than 2 months, stopping this medication too suddenly might cause your stomach to produce more acid (acid rebound), which worsen your GERD symptoms. Your healthcare team can recommend ways to stop dexlansoprazole (Dexilant) that minimizes acid rebound. For example, one strategy is to take this medication as needed when your symptoms flare up. Another strategy is to use other GERD medications to treat your rebound symptoms. If your symptoms don't go away or seem to get worse after stopping dexlansoprazole (Dexilant), let your PCP know.
                Can dexlansoprazole (Dexilant) be taken long term?
                In most cases, dexlansoprazole (Dexilant) isn't meant to be taken for longer than 1 to 2 months at a time. It's important to take dexlansoprazole (Dexilant) only for as long as your PCP directed. Continuing to take dexlansoprazole (Dexilant) longer than recommended can raise your risk of certain health concerns, such as bone fractures and low magnesium levels. Talk with your PCP if you're not sure how long to take dexlansoprazole (Dexilant).
                Does dexlansoprazole (Dexilant) cause cancer?
                There isn't a strong link between dexlansoprazole (Dexilant) and cancer. Some observational studies suggest there taking PPIs long-term can raise the risk of stomach cancer for people who have H. pylori infections and existing stomach injury. Other studies suggest that PPIs raise the level of a hormone called gastrin, which might be linked to stomach cancer. But more research is needed to understand the connection between PPIs, including dexlansoprazole (Dexilant), and cancer. As a precaution, your PCP will likely recommend that you take dexlansoprazole (Dexilant) for the shortest time needed to treat your symptoms. Let your PCP know if you're concerned about the possible risk of cancer with PPIs.
                Can I take dexlansoprazole (Dexilant) and omeprazole (Prilosec) together?
                Don't take dexlansoprazole (Dexilant) along with other PPIs, such as omeprazole (Prilosec). These medications work in very similar ways to lower stomach acid levels and taking them together can raise the risk of side effects, such as diarrhea and nausea. If dexlansoprazole (Dexilant) alone isn't relieving your symptoms, talk to your care team about other treatment options.
                Is dexlansoprazole (Dexilant) available as a generic?
                Yes, dexlansoprazole (Dexilant) is available as a lower-cost generic medication.
                Is dexlansoprazole (Dexilant) over the counter?
                No, dexlansoprazole (Dexilant) isn't available over the counter. You'll need a prescription from a healthcare professional for this medication. Ask your pharmacist if you're looking for a PPI that can be found over the counter.
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                What are the risks and warnings for Dexlansoprazole (Dexilant)?

                Dexlansoprazole (Dexilant) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Risk of hiding symptoms of a more serious condition

                Frequent episodes of heartburn can be a symptom of stomach cancer. If your heartburn gets worse or comes back after taking dexlansoprazole (Dexilant), let your PCP know. Also contact your PCP if you have poor appetite, unexplained weight loss, or weakness along with your heartburn. They can check if there are other serious medical problems going on.

                risk-warning

                Sudden kidney problems

                Some people taking PPIs like dexlansoprazole (Dexilant) have had sudden kidney problems. These problems can happen at any point during treatment. Talk with your prescriber if you're urinating more or less than usual, feel nauseous or weak, or have a fever, rash, or joint pain. These can be symptoms of kidney problems.

                risk-warning

                Severe infectious diarrhea

                • Risk factors: Older people | Recent stay at a hospital or nursing home | People with a weakened immune system (e.g. cancer)

                  Some clinical studies showed that PPIs, such as dexlansoprazole (Dexilant), can raise the risk of getting a bacterial infection called Clostridioides difficile (C. diff). This infection can cause severe diarrhea. Your risk is higher if you're over 65 years old, have recently stayed at a hospital or nursing home, or have a weakened immune system. To lower your risk of C. diff diarrhea, only take dexlansoprazole (Dexilant) for as long as recommended by your PCP. If you experience severe or watery diarrhea, fever, belly pain, loss of appetite, or nausea, let your PCP know right away.

                  risk-warning

                  Bone fractures

                  • Risk factors: Taking high doses of dexlansoprazole (Dexilant) | Taking dexlansoprazole (Dexilant) for longer than a year | Older adult

                    PPIs, like dexlansoprazole (Dexilant), might raise the risk of bone fractures in the hip, wrist, or spine. Your risk is higher if you take more than one dose of dexlansoprazole (Dexilant) per day or if you take it for more than a year. To prevent the risk of bone fracture, your PCP will prescribe dexlansoprazole (Dexilant) for the shortest time needed to treat your symptoms. If you've had bone fractures before or have osteoporosis (weak bones), talk to your PCP about your risk before starting this medication.

                    risk-warning

                    Skin reactions

                    PPIs, such as dexlansoprazole (Dexilant), have rarely caused serious skin reactions. These reactions include Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Symptoms can include fever, body aches, rash, peeling skin, painful blisters, and swelling of the face. If you notice any of these symptoms, get medical help immediately.

                    risk-warning

                    Lupus

                    Some people taking PPIs, like dexlansoprazole (Dexilant), developed new or worsening lupus. This is a condition where your immune system attacks your own body. Lupus symptoms can occur any time during treatment with dexlansoprazole (Dexilant). Some typical symptoms include joint pain or rash, but they often improve within 1 to 3 months of stopping this medication. If you experience any lupus symptoms while taking dexlansoprazole (Dexilant), stop the medication and contact your PCP.

                    risk-warning

                    Low vitamin B12 and magnesium levels

                    • Risk factor: Long-term use | Taking medications that can lower magnesium or vitamin B12 levels

                      Taking acid-lowering medications, like dexlansoprazole (Dexilant), for a long period of time can cause your vitamin B12 levels to drop. Dexlansoprazole (Dexilant) lowers the amount of acid in your stomach, which is needed for vitamin B12 absorption. If you've been taking this medication for longer than 3 years, or if you have symptoms of vitamin B12 deficiency (e.g., dizziness, muscle weakness, pale skin, tiredness, tingling in arms or legs), talk to your PCP.

                      Taking dexlansoprazole (Dexilant) can also lower your magnesium levels. This can happen 3 months after taking dexlansoprazole (Dexilant), but it's more likely to happen after a year of treatment. Low magnesium levels can sometimes lead to other electrolyte problems. Your PCP might check your blood before and during treatment with dexlansoprazole (Dexilant) to make sure your electrolyte levels are in the normal range. Watch for symptoms of electrolyte problems like irregular heart rate, muscle cramps, and tremors. Let your PCP know right away if they occur.

                      risk-warning

                      Interaction with other medications

                      Some medications can interfere with how your body gets rid of dexlansoprazole (Dexilant). Depending on if they boost or block how dexlansoprazole (Dexilant) gets removed, these medications can affect the amount of dexlansoprazole (Dexilant) in your body, how well it works, and the risk of side effects. For example, St. John’s Wort and rifampin (Rifadin) can lower the amount of dexlansoprazole (Dexilant) in your body and cause the medication to not work as well. Avoid these medications while taking dexlansoprazole (Dexilant).

                      Dexlansoprazole (Dexilant) can also interfere with how other medications work. Avoid taking dexlansoprazole (Dexilant) with medications that contain rilpivirine, such as Edurant (rilpivirine) and Cabenuva (cabotegravir / rilpivirine). Dexlansoprazole (Dexilant) causes these medications to not work as well, which can worsen human immunodeficiency virus (HIV) infection. In addition, dexlansoprazole (Dexilant) can raise the risk of methotrexate toxicity when taken together with methotrexate.

                      dosage

                      Dexlansoprazole (Dexilant) dosage forms

                      The average cost for 30 capsules of 60mg of Dexlansoprazole (Dexilant) is $304.63 with a free GoodRx coupon. This is 19.54% off the average retail price of $378.59.
                      capsule
                      Capsule
                      DosageQuantityPrice as low asPrice per unit
                      30mg30 capsules$304.15$10.14
                      60mg30 capsules$304.63$10.15

                      Typical dosing for Dexlansoprazole (Dexilant)

                      Dexlansoprazole (Dexilant) should only be used in adults and children 12 years of age and older:

                      • Treatment of EE: The typical dose is 60 mg by mouth once daily for up to 2 months.

                      • Heartburn relief and maintenance of healed EE: The typical dose is 30 mg by mouth once daily for up to 6 months in adults and up to 4 months for children between 12-17 years old.

                      • GERD: The typical dose is 30 mg by mouth once daily for up to 1 month.

                      Your dose of dexlansoprazole (Dexilant) might differ if you have liver problems.

                      interactions

                      Interactions between Dexlansoprazole (Dexilant) and other drugs

                      Dexlansoprazole (Dexilant) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Dexlansoprazole (Dexilant). Please note that only the generic name of each medication is listed below.

                      Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                      • Rilpivirine

                      Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                      Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                      drug-cost

                      How much does Dexlansoprazole (Dexilant) cost?

                      To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
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                      contraindications-icon

                      Dexlansoprazole (Dexilant) contraindications

                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Dexlansoprazole (Dexilant) will not be safe for you to take.
                      alternatives

                      What are alternatives to Dexlansoprazole (Dexilant)?

                      There are a number of medications that your doctor can prescribe in place of Dexlansoprazole (Dexilant). Compare a few possible alternatives below.
                      Dexlansoprazole (Dexilant)
                      Used for:
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                      Lansoprazole (Prevacid)
                      Used for:
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                      Esomeprazole (Nexium)
                      Used for:

                      • Heartburn — OTC only

                      • Lower the risk of stomach ulcer due to nonsteroidal anti-inflammatory drugs (NSAID)

                      • Lower the risk of duodenal ulcer caused by Helicobacter pylori (H. pylori) infection

                      • Other medical conditions that cause too much stomach acid (e.g., Zollinger-Ellison syndrome)

                      • Gastroesophageal reflux disease (GERD)

                      • Inflamed esophagus due to GERD

                      $10.20 Lowest GoodRx priceView Prices
                      latest news

                      What is the latest news about Dexlansoprazole (Dexilant)?

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                      Famotidine, a medication used to treat heartburn and stomach ulcers, has recently gone into shortage. The shortage could be due to recalls of other heartburn medications, use of the drug in COVID-19 treatment research, or a combination of both. People who are not able to obtain famotidine can look into alternative medications such as nizatidine (Axid), cimetidine (Tagamet), and cimetidine HB (Tagamet HB).

                      Famotidine in Shortage Due to Heartburn Medication Recalls and COVID-19 Research

                      Famotidine, a medication used to treat heartburn and stomach ulcers, has recently gone into shortage. The shortage could be due to recalls of other heartburn medications, use of the drug in COVID-19 treatment research, or a combination of both. People who are not able to obtain famotidine can look into alternative medications such as nizatidine (Axid), cimetidine (Tagamet), and cimetidine HB (Tagamet HB).
                      Brand-only drugs like Restasis, Eliquis and Lyrica can cost over $500 for a month’s supply, and they don’t have cheaper generic alternatives (yet). FDA drug approval initiatives will hopefully bring many generics to the market soon. In fact, 40+ expensive brand drugs are expected to go generic in the next five years.

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                      images

                      Dexlansoprazole (Dexilant) images

                      Blue T002 - Dexlansoprazole 60mg Delayed-Release Capsule
                      This medicine is Blue Capsule Imprinted With "T002".Blue T002 - Dexlansoprazole 60mg Delayed-Release Capsule
                      Blue T002 - Dexlansoprazole 60mg Delayed-Release Capsule
                      This medicine is Blue Capsule Imprinted With "T002".Blue T002 - Dexlansoprazole 60mg Delayed-Release Capsule

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                      References

                      Best studies we found

                      American Cancer Society. (2021). Signs and symptoms of stomach cancer.

                      Centers for Disease Control and Prevention. (2022). What is C. diff?

                      Cheung, K.S., et al. (2019). Long-term use of proton-pump inhibitors and risk of gastric cancer: a review of the current evidence. Therapeutic Advances in Gastroenterology.

                      View All References (5)

                      National Institutes of Health. (2022). Vitamin B12 fact sheet for consumers.

                      O'Brien, F. (2022). Tubulointerstitial nephritis. Merck Manual Consumer Version.

                      Poly, T.N., et al. (2022). Proton Pump Inhibitor Use and Risk of Gastric Cancer: Current Evidence from Epidemiological Studies and Critical Appraisal. Cancers.

                      Smith, J.P., et al. (2017). Gastrin and Gastric Cancer. Cellular and Molecular Gastroenterology and Hepatology.

                      TWI PHARMACEUTICALS, INC. (2023). DEXLANSOPRAZOLE DELAYED RELEASE- dexlansoprazole capsule, delayed release [package insert]. DailyMed.

                      GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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