Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Esomeprazole (Nexium) and calcium carbonate (Tums) are both used to treat heartburn, but they work in different ways and have different uses. Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production and is available both over-the-counter and by prescription. It is used for conditions like GERD, stomach ulcers, and Zollinger-Ellison syndrome. It takes a few days to feel its full effects and is taken before meals. On the other hand, calcium carbonate is an antacid that neutralizes stomach acid and provides quick relief within minutes. It is available over-the-counter and is also used to treat indigestion and sour stomach. Esomeprazole can have more serious side effects like bone fractures and low magnesium levels with long-term use, while calcium carbonate's main side effect is constipation. Additionally, calcium carbonate can be used as a calcium supplement, whereas esomeprazole cannot.
Esomeprazole (Nexium)
Calcium carbonate
Esomeprazole (Nexium)
Calcium carbonate
Summary of Nexium vs. Tums
Summary for PPI
Esomeprazole (Nexium) is a medication used to treat conditions that are caused by too much stomach acid, such as heartburn or acid reflux. It's available both with a prescription and over the counter (OTC). Take esomeprazole (Nexium) an hour before a meal so that it can start working before you eat. It can take a couple days for you to feel its full effects, so consider taking other quick-acting antacids in the meantime until the medication effect kicks in.
Summary for Antacid
Calcium carbonate is an antacid. It's mainly used to relieve symptoms of acid reflux, such as heartburn and indigestion, for adults and children. Sometimes, providers might prescribe it as a supplement to prevent calcium deficiency. Calcium carbonate is available over the counter in several different formulations, including chewable tablets and oral solutions. Side effects from calcium carbonate are rare, but some people have reported constipation.
Indications of Nexium vs. Tums
Indications for
For adults only:
•Heartburn — OTC only
•Lower the risk of stomach ulcer due to nonsteroidal anti-inflammatory drugs (NSAID)
•Lower the risk of duodenal ulcer caused by Helicobacter pylori (H. pylori) infection