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Compare Nexium vs. Tums

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Esomeprazole (Nexium) and calcium carbonate (Tums) are both used to treat heartburn, but they work in different ways and have different uses. Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production and is available both over-the-counter and by prescription. It is used for conditions like GERD, stomach ulcers, and Zollinger-Ellison syndrome. It takes a few days to feel its full effects and is taken before meals. On the other hand, calcium carbonate is an antacid that neutralizes stomach acid and provides quick relief within minutes. It is available over-the-counter and is also used to treat indigestion and sour stomach. Esomeprazole can have more serious side effects like bone fractures and low magnesium levels with long-term use, while calcium carbonate's main side effect is constipation. Additionally, calcium carbonate can be used as a calcium supplement, whereas esomeprazole cannot.

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