Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Alka-Seltzer (citric acid/aspirin/sodium bicarbonate) and calcium carbonate (Tums) are both over-the-counter medications used to treat heartburn and indigestion, but they have some key differences. Alka-Seltzer is a combination of three ingredients: citric acid and sodium bicarbonate, which are antacids, and aspirin, which is a pain reliever. It comes in dissolvable tablets that you mix with water. On the other hand, calcium carbonate is a single-ingredient antacid available in chewable tablets and oral suspensions. Alka-Seltzer can also help with headaches and body aches due to its aspirin content, while calcium carbonate is sometimes used as a calcium supplement. Alka-Seltzer is not recommended for children under 12 or for pregnant women due to the aspirin, whereas calcium carbonate has specific formulations for children and is generally safe during pregnancy. Additionally, Alka-Seltzer carries a risk of stomach bleeding and ulcers, especially in older adults or those with certain health conditions, while calcium carbonate can cause constipation and, in rare cases, high blood calcium levels.
Alka-seltzer
Calcium carbonate
Alka-seltzer
Calcium carbonate
Summary of Alka-Seltzer vs. Tums
Summary for Antacid / NSAID
Alka-Seltzer is a medication used to treat symptoms of heartburn, such as upset stomach and headache. While there are multiple products under this brand, this page focuses on the combination medication containing 3 active ingredients: citric acid, sodium bicarbonate, and aspirin. It comes as tablets that are dissolved in water. You drink the mixture by mouth, typically every 4-6 hours as needed.
Summary for Antacid
Calcium carbonate is an antacid. It's mainly used to relieve symptoms of acid reflux, such as heartburn and indigestion, for adults and children. Sometimes, providers might prescribe it as a supplement to prevent calcium deficiency. Calcium carbonate is available over the counter in several different formulations, including chewable tablets and oral solutions. Side effects from calcium carbonate are rare, but some people have reported constipation.
Indications of Alka-Seltzer vs. Tums
Indications for
•Heartburn, indigestion, and sour stomach with headache, body aches, or pain
•Upset stomach and headache from having too much food or drink