Key takeaways
Bromfed DM (brompheniramine/pseudoephedrine/dextromethorphan) and Nyquil Cold and Flu (acetaminophen/dextromethorphan/doxylamine) are both used to relieve symptoms of the common cold, such as cough and runny nose. However, they have some important differences. Bromfed DM combines an antihistamine, a decongestant, and a cough suppressant, while Nyquil Cold and Flu includes an analgesic, a cough suppressant, and an antihistamine. Bromfed DM is available by prescription only and comes as a liquid, whereas Nyquil Cold and Flu is available over-the-counter in both liquid and capsule forms. Bromfed DM is typically taken every 4 hours, while Nyquil Cold and Flu is taken every 6 hours. Common side effects of both medications include sleepiness and dizziness. If you have other health conditions or take other medications, talk to your prescriber or pharmacist before taking either medication.
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