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Compare Alka-Seltzer vs. Mylanta Maximum Strength

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Alka-Seltzer (citric acid/aspirin/sodium bicarbonate) and Mylanta Maximum Strength (aluminum hydroxide/magnesium hydroxide/simethicone) are both over-the-counter medications used to relieve heartburn and indigestion. However, they belong to different medication classes and have distinct differences. Alka-Seltzer combines antacids with aspirin, an NSAID, to also address pain and inflammation, while Mylanta Maximum Strength includes antacids and simethicone, an antiflatulent, to relieve gas. Alka-Seltzer is available as dissolvable tablets, whereas Mylanta Maximum Strength is a liquid suspension. Alka-Seltzer is not recommended for children under 12 or during pregnancy due to the risk of Reye's syndrome and potential harm from aspirin. Mylanta Maximum Strength, on the other hand, is not recommended during pregnancy due to its aluminum content and potential for causing diarrhea. Common side effects of Alka-Seltzer include stomach bleeding and ulcers, while Mylanta Maximum Strength may cause diarrhea and nausea. Additionally, Alka-Seltzer can interact with blood thinners, increasing bleeding risk, whereas Mylanta Maximum Strength can interfere with the absorption of other medications.

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