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Compare Zinplava vs. Vancomycin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Zinplava (bezlotoxumab)
    Vancomycin injection
  • Zinplava (bezlotoxumab)
    Vancomycin injection

  • Summary of Zinplava vs. Vancomycin

    Summary for Biologic
    Prescription only

    Zinplava (bezlotoxumab) is a medication used to prevent repeat infection from a bacteria called Clostridioides difficile (C. diff). It's given as an injection into the veins for one dose only.

    Summary for Glycopeptide antibiotic
    Prescription only

    Vancomycin injection is an antibiotic used to treat some serious bacterial infections in adults and children. It treats bacterial infections in the bloodstream, skin, bone, heart, and lungs. This medication is given as an injection into your vein by a healthcare professional. It's usually infused 2 to 4 times a day. Your prescriber will check the vancomycin levels in your blood to make sure the dose is safe and works well for you. Side effects can include diarrhea and dizziness. If given too fast, it has a risk of causing a serious infusion reaction (previously known as red man syndrome).

  • Indications of Zinplava vs. Vancomycin

    Indications for
    •Prevention of another C. diff infection (CDI) in high-risk adults who are taking antibiotics for CDI
    Indications for

    Treatment of certain serious bacterial infections, including:

    •Bloodstream infection (septicemia)
    •Heart infection (infective endocarditis)
    •Skin infections
    •Bone infections
    •Lower respiratory tract infections

  • Pros and Cons of Zinplava vs. Vancomycin

    Pros and Const for Biologic
    Pros
    •Works well to prevent CDIs
    •Given as a single dose
    •No known drug interactions
    Cons
    •Only used for preventing CDI from happening again (not for treatment)
    •Given as an IV injection by a healthcare provider
    •Brand name only, so might be expensive
    Pros and Const for Glycopeptide antibiotic
    Pros
    •Can treat certain hard-to-treat bacterial infections
    •Approved for adults and children of most ages
    •A possible option for people with a penicillin allergy
    Cons
    •Can raise the risk of kidney damage
    •Need regular blood work and tests to check for appropriate dosing and side effects
    •Risk of a serious infusion reaction if injected into the vein too quickly

  • Common Side Effects of Zinplava vs. Vancomycin

    Common Side Effects for
    •Nausea (7%)
    •Fever (5%)
    •Headache (4%)
    Common Side Effects for
    •Pain and redness at the injection site

  • Warnings of Zinplava vs. Vancomycin

    Common Side Effects for
    •Heart failure
    Common Side Effects for
    •Infusion reactions
    •Sudden kidney problems
    •Hearing problems
    •Severe skin reactions
    •Severe infectious diarrhea
    •Risk of low white blood cell counts

  • Prices with our coupons for Zinplava vs. Vancomycin

    Learn more about Zinplava
    Learn more about Vancomycin injection

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