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Compare Zinplava vs. Vancomycin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Zinplava (bezlotoxumab)
    Vancomycin injection
  • Zinplava (bezlotoxumab)
    Vancomycin injection

  • Summary of Zinplava vs. Vancomycin

    Summary for Biologic
    Prescription only

    Zinplava (bezlotoxumab) is a medication used to prevent repeat infection from a bacteria called Clostridioides difficile (C. diff). It's given as an injection into the veins for one dose only.

    Summary for Glycopeptide
    Prescription only

    Vancomycin injection is an antibiotic medication used to treat different serious infections, including those that affect your bloodstream and heart. It's given by a healthcare provider as an intravenous (IV) infusion, typically 2 to 4 times a day depending on the type of infection. Your provider will check vancomycin levels through blood work and adjust your dose if needed. One possible side effect of vancomycin injection is vancomycin flushing syndrome (previously known as red man syndrome), a serious allergic reaction that can happen if you receive the infusion too quickly.

  • Indications of Zinplava vs. Vancomycin

    Indications for
    •Prevention of another C. diff infection (CDI) in high-risk adults who are taking antibiotics for CDI
    Indications for

    Treatment of certain serious bacterial infections, including:

    •Bloodstream infection (septicemia)
    •Heart infection (infective endocarditis)
    •Skin infections
    •Bone infections (osteomyelitis)
    •Lung infections (lower respiratory tract infections)

  • Pros and Cons of Zinplava vs. Vancomycin

    Pros and Const for Biologic
    Pros
    •Works well to prevent CDIs
    •Given as a single dose
    •No known drug interactions
    Cons
    •Only used for preventing CDI from happening again (not for treatment)
    •Given as an IV injection by a healthcare provider
    •Brand name only, so might be expensive
    Pros and Const for Glycopeptide
    Pros
    •Can treat certain hard-to-treat infections
    •Can be given to children younger than 1 month of age
    •A possible option for people with penicillin allergy
    Cons
    •Can raise the risk of kidney damage
    •Need regular blood work and lab tests to check for appropriate dose and side effects
    •Risk of serious allergic reactions if injected into the veins too quickly

  • Common Side Effects of Zinplava vs. Vancomycin

    Common Side Effects for
    •Nausea (7%)
    •Fever (5%)
    •Headache (4%)
    Common Side Effects for
    •Pain and redness at the injection site

  • Warnings of Zinplava vs. Vancomycin

    Common Side Effects for
    •Heart failure
    Common Side Effects for
    •Sudden kidney problems
    •Hearing problems
    •Severe skin reactions
    •Infusion-related reactions
    •Risk of low white blood cells
    •Severe infectious diarrhea

  • Prices with our coupons for Zinplava vs. Vancomycin

    Learn more about Zinplava
    Learn more about Vancomycin injection

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