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Yupelri vs. Atrovent HFA

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Yupelri

(revefenacin)

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Atrovent HFA

(ipratropium)

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Summary for Yupelri

Prescription only

Yupelri (revefenacin) is an inhalation solution that's used to treat adults with chronic obstructive pulmonary disease (COPD). It belongs to the drug class called long-acting muscarinic antagonists, or LAMAs. Yupelri (revefenacin) is inhaled through the mouth once a day using a nebulizer machine. Some possible side effects include headache and cough. Yupelri (revefenacin) is a brand-name medication; there's currently no generic version available.

Indications for Yupelri

Pros and Cons for Yupelri

Pros

  • Only taken once a day
  • Works quickly (within 5 minutes) and lasts the whole day
  • Easy to breathe in; there isn't as much timing and technique needed like for COPD inhalers

Cons

  • Must set up the nebulizer machine before each dose
  • Takes about 8 minutes to take a full dose
  • Not a good option for people with liver damage because of higher risk of side effects

Common Side Effects for Yupelri

Warnings for Yupelri

  • Sudden trouble breathing
  • Eye problems
  • Problems with urination
  • Allergic reactions

Summary for Atrovent HFA

Prescription only

Atrovent HFA (ipratropium) is a short-acting inhaled anticholinergic medication used to help with difficulty breathing in people with chronic obstructive pulmonary disease (COPD). This medication comes in an inhaler. Typically, you breathe in 2 inhalations, 4 times a day. You should use Atrovent HFA (ipratropium) regularly every day in order it for it to keep your COPD symptoms under control. It's not meant to be used as a rescue inhaler.

Indications for Atrovent HFA

Pros and Cons for Atrovent HFA

Pros

  • Works well as a maintenance treatment for COPD
  • Small inhaler, so easy to take with you, compared to the nebulized ipratropium
  • Not many interactions with other medications

Cons

  • Need to use 2 puffs (inhalations) every 4 hours
  • Not a rescue inhaler
  • It's not completely clear how safe it is for pregnant or breastfeeding females

Common Side Effects for Atrovent HFA

  • Cough and other symptoms of bronchitis (10-23%)
  • Worsened COPD symptoms (8-23%)
  • Trouble breathing (7-8%)
  • Tiredness, chills, and other flu-like symptoms (4-8%)
  • Headache (6-7%)
  • Back pain (2-7%)

Warnings for Atrovent HFA

  • Severe allergic reactions
  • Narrowing of your airways (bronchospasm)
  • Risk of eye and vision problems
  • Trouble urinating

Prices with our coupons for Yupelri vs. Atrovent HFA

Price Card Drug Icon
Yupelri1 carton / 30 vials of 175mcg/3ml
$1,579.98$2,018.19
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Price Card Drug Icon
Ipratropium1 hfa inhaler / 12.9g of 17mcg
$86.95$368.01
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