Compare Xyzal Allergy vs. Flonase

Levocetirizine (Xyzal Allergy 24HR) and fluticasone nasal spray (Flonase Allergy Relief, Flonase Sensimist) are both used to treat allergy symptoms, such as runny nose and sneezing. However, they belong to different medication classes. Levocetirizine is an antihistamine that works by blocking histamine, a chemical in your body that causes allergy symptoms. It is available in tablet and liquid forms and can be taken once daily, either over-the-counter or by prescription. On the other hand, fluticasone nasal spray is a corticosteroid that reduces inflammation in your nose. It is available as a nasal spray and must be used daily for the best results. While levocetirizine can cause drowsiness and cold-like symptoms, fluticasone may lead to nosebleeds and headaches. Additionally, fluticasone nasal spray can slow growth in children if used for more than two months a year. Both medications are available in generic forms, but levocetirizine is more likely to cause drowsiness compared to fluticasone.